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MGP000591

Record overview

MGPD IDMGP000591
Gene ID1207
SpeciesHomo sapiens (Human)
Gene Namechloride channel, nucleotide-sensitive, 1A
Gene Symbol CLNS1A
SynonymsCLCI; ICln; CLNS1B;
Alternate namesmethylosome subunit pICln; i(Cln); reticulocyte pICln; reticulocyte protein ICln; chloride channel regulatory protein; chloride ion current inducer protein; chloride channel, nucleotide sensitive 1A; chloride conductance regulatory protein ICln;
Chromosome11
Map Location11q13.5-q14
SummaryThis gene encodes a protein that functions in multiple regulatory pathways. The encoded protein complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. The protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of this gene are found on chromosomes 1, 4 and 6. [provided by RefSeq, Feb 2009]
OrthologsView orthologs and multiple alignments for CLNS1A

Proteins

methylosome subunit pICln
Refseq ID:NP_001284
Protein GI:4502891
UniProt ID:P54105
mRNA ID:NM_001293
Length:237
RefSeq Status:
MSFLKSFPPPGPAEGLLRQQPDTEAVLNGKGLGTGTLYIAESRLSWLDGSGLGFSLEYPTISLHALSRDRSDCLGEHLYVMVNAKFEEESKEPVADEEEE
DSDDDVEPITEFRFVPSDKSALEAMFTAMCECQALHPDPEDEDSDDYDGEEYDVEAHEQGQGDIPTFYTYEEGLSHLTAEGQATLERLEGMLSQSVSSQY
NMAGVRTEDSIRDYEDGMEVDTTPTVAGQFEDADVDH
 
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