MGP Database

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MGP000594

UniProt Annotations

Entry Information
Gene Nameclathrin, light chain B
Protein EntryCLCB_HUMAN
UniProt IDP09497
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=Brain; IsoId=P09497-1; Sequence=Displayed; Name=Non-brain; IsoId=P09497-2; Sequence=VSP_001098;
FunctionClathrin is the major protein of the polyhedral coat of coated pits and vesicles.
SimilarityBelongs to the clathrin light chain family. {ECO:0000305}.
Subcellular LocationCytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
SubunitClathrin coats are formed from molecules containing 3 heavy chains and 3 light chains. Interacts (via N-terminus) with HIP1. Interacts with HIP1R. {ECO:0000269|PubMed:11889126, ECO:0000269|PubMed:15533940}.
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