MGP Database

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MGP000600

Ontology/Pathway Information

Entrez Gene ID1234
Gene Namechemokine (C-C motif) receptor 5 (gene/pseudogene)
Gene Symbol CCR5
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:UniProtKBCcell surface
GO:0005737 TAS:ProtIncCcytoplasm
GO:0005768 IDA:UniProtKBCendosome
GO:0009897 IDA:UniProtKBCexternal side of plasma membrane
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0003779 IDA:UniProtKBFactin binding
GO:0019957 IPI:UniProtKBFC-C chemokine binding
GO:0016493 NAS:UniProtKBFC-C chemokine receptor activity
GO:0071791 IPI:UniProtKBFchemokine (C-C motif) ligand 5 binding
GO:0004950 TAS:ProtIncFchemokine receptor activity
GO:0015026 TAS:ProtIncFcoreceptor activity
GO:0004435 TAS:ProtIncFphosphatidylinositol phospholipase C activity
GO:0006816 IDA:UniProtKBPcalcium ion transport
GO:0019722 IDA:UniProtKBPcalcium-mediated signaling
GO:0007267 IDA:UniProtKBPcell-cell signaling
GO:0007166 TAS:ProtIncPcell surface receptor signaling pathway
GO:0006968 TAS:ProtIncPcellular defense response
GO:0071222 IEP:UniProtKBPcellular response to lipopolysaccharide
GO:0070098 IDA:GOCPchemokine-mediated signaling pathway
GO:0006935 TAS:ProtIncPchemotaxis
GO:0002407 TAS:BHF-UCLPdendritic cell chemotaxis
GO:0030260 TAS:ReactomePentry into host cell
GO:0007186 IMP:UniProtKBPG-protein coupled receptor signaling pathway
GO:0006955 TAS:ProtIncPimmune response
GO:0006954 TAS:ProtIncPinflammatory response
GO:0000165 IEP:UniProtKBPMAPK cascade
GO:0007204 TAS:ProtIncPpositive regulation of cytosolic calcium ion concentration
GO:0014808 IDA:UniProtKBPrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0070723 IMP:UniProtKBPresponse to cholesterol
GO:0023052 IEP:UniProtKBPsignaling
GO:0016032 TAS:ReactomePviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6903Binding and entry of HIV virion
REACT_15344Chemokine receptors bind chemokines
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_6266Early Phase of HIV Life Cycle
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_6185HIV Infection
REACT_6256HIV Life Cycle
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
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