MGP Database

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MGP000606

Ontology/Pathway Information

Entrez Gene ID1244
Gene NameATP-binding cassette, sub-family C (CFTR/MRP), member 2
Gene Symbol ABCC2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016324 IDA:UniProtKBCapical plasma membrane
GO:0009986 IDA:UniProtKBCcell surface
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0046581 IEA:EnsemblCintercellular canaliculus
GO:0005886 TAS:ReactomeCplasma membrane
GO:0042626 TAS:ProtIncFATPase activity, coupled to transmembrane movement of substances
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0008514 TAS:ProtIncForganic anion transmembrane transporter activity
GO:0030644 IEA:EnsemblPcellular chloride ion homeostasis
GO:0006855 IEA:EnsemblPdrug transmembrane transport
GO:0015732 IEA:EnsemblPprostaglandin transport
GO:0046685 IEA:EnsemblPresponse to arsenic-containing substance
GO:0043627 IEA:EnsemblPresponse to estrogen
GO:0009408 IEA:EnsemblPresponse to heat
GO:0031427 IEA:EnsemblPresponse to methotrexate
GO:0006979 IEA:EnsemblPresponse to oxidative stress
GO:0070327 IEA:EnsemblPthyroid hormone transport
GO:0055085 TAS:ReactomePtransmembrane transport
GO:0006810 TAS:ProtIncPtransport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15480ABC-family proteins mediated transport
REACT_15518Transmembrane transport of small molecules
SMP Pathway Links
SMP IDDescription
SMP00435Docetaxel Action Pathway
SMP00650Doxorubicin Metabolism Pathway
SMP00433Irinotecan Action Pathway
SMP00600Irinotecan Metabolism Pathway
SMP00649Lamivudine Metabolism Pathway
SMP00652Mycophenolic Acid Metabolism Pathway
SMP00434Paclitaxel Action Pathway
SMP00637Tramadol Metabolism Pathway
SMP00436Vinblastine Action Pathway
SMP00437Vincristine Action Pathway
SMP00438Vindesine Action Pathway
SMP00439Vinorelbine Action Pathway
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