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MGP Database

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MGP000612

Ontology/Pathway Information

Entrez Gene ID	1269
Gene Name	cannabinoid receptor 2 (macrophage)
Gene Symbol	CNR2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0030425	IEA:UniProtKB-SubCell	C	dendrite
GO:0031234	IEA:Ensembl	C	extrinsic component of cytoplasmic side of plasma membrane
GO:0005887	TAS:ProtInc	C	integral component of plasma membrane
GO:0043204	IEA:UniProtKB-SubCell	C	perikaryon
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0004949	TAS:ProtInc	F	cannabinoid receptor activity
GO:0038171	TAS:GOC	P	cannabinoid signaling pathway
GO:0007187	TAS:ProtInc	P	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0006955	TAS:ProtInc	P	immune response
GO:0006954	IEA:UniProtKB-KW	P	inflammatory response
GO:0045759	IEA:Ensembl	P	negative regulation of action potential
GO:0050728	IEA:Ensembl	P	negative regulation of inflammatory response
GO:0033004	IEA:Ensembl	P	negative regulation of mast cell activation
GO:0051001	IEA:Ensembl	P	negative regulation of nitric-oxide synthase activity
GO:0032229	IEA:Ensembl	P	negative regulation of synaptic transmission, GABAergic
GO:0001975	IEA:Ensembl	P	response to amphetamine
GO:0032496	IEA:Ensembl	P	response to lipopolysaccharide
GO:0019233	IEA:Ensembl	P	sensory perception of pain

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_14828	Class A/1 (Rhodopsin-like receptors)
REACT_267874	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125	Disease
REACT_19231	G alpha (i) signalling events
REACT_19184	GPCR downstream signaling
REACT_21340	GPCR ligand binding
REACT_267615	Metabolic disorders of biological oxidation enzymes
REACT_14797	Signaling by GPCR
REACT_111102	Signal Transduction