MGP Database

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MGP000615

Ontology/Pathway Information

Entrez Gene ID1278
Gene Namecollagen, type I, alpha 2
Gene Symbol COL1A2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005584 IDA:UniProtKBCcollagen type I trimer
GO:0005788 TAS:ReactomeCendoplasmic reticulum lumen
GO:0031012 IDA:UniProtKBCextracellular matrix
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005201 NAS:UniProtKBFextracellular matrix structural constituent
GO:0042802 IDA:UniProtKBFidentical protein binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0048407 IDA:MGIFplatelet-derived growth factor binding
GO:0030674 IMP:UniProtKBFprotein binding, bridging
GO:0007596 TAS:ReactomePblood coagulation
GO:0001568 IMP:UniProtKBPblood vessel development
GO:0071230 IEA:EnsemblPcellular response to amino acid stimulus
GO:0030574 TAS:ReactomePcollagen catabolic process
GO:0030199 IMP:UniProtKBPcollagen fibril organization
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0050900 TAS:ReactomePleukocyte migration
GO:0042476 NAS:UniProtKBPodontogenesis
GO:0030168 TAS:ReactomePplatelet activation
GO:0070208 IEA:EnsemblPprotein heterotrimerization
GO:0008217 IMP:UniProtKBPregulation of blood pressure
GO:0007266 IDA:UniProtKBPRho protein signal transduction
GO:0001501 IMP:UniProtKBPskeletal system development
GO:0043589 IMP:UniProtKBPskin morphogenesis
GO:0007179 IDA:UniProtKBPtransforming growth factor beta receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_150268Anchoring fibril formation
REACT_150180Assembly of collagen fibrils and other multimeric structures
REACT_160300Binding and Uptake of Ligands by Scavenger Receptors
REACT_12051Cell surface interactions at the vascular wall
REACT_121139Collagen biosynthesis and modifying enzymes
REACT_150401Collagen degradation
REACT_120729Collagen formation
REACT_150206Crosslinking of collagen fibrils
REACT_118572Degradation of the extracellular matrix
REACT_163906ECM proteoglycans
REACT_118779Extracellular matrix organization
REACT_1695GPVI-mediated activation cascade
REACT_604Hemostasis
REACT_13552Integrin cell surface interactions
REACT_163874Non-integrin membrane-ECM interactions
REACT_798Platelet activation, signaling and aggregation
REACT_1230Platelet Adhesion to exposed collagen
REACT_163699Scavenging by Class A Receptors
REACT_163942Syndecan interactions
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