MGP Database

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MGP000619

Ontology/Pathway Information

Entrez Gene ID1285
Gene Namecollagen, type IV, alpha 3 (Goodpasture antigen)
Gene Symbol COL4A3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005604 IDA:UniProtKBCbasement membrane
GO:0005587 IDA:UniProtKBCcollagen type IV trimer
GO:0005788 TAS:ReactomeCendoplasmic reticulum lumen
GO:0005576 TAS:ReactomeCextracellular region
GO:0005201 IEA:InterProFextracellular matrix structural constituent
GO:0005178 IDA:UniProtKBFintegrin binding
GO:0008191 NAS:UniProtKBFmetalloendopeptidase inhibitor activity
GO:0005198 NAS:ProtIncFstructural molecule activity
GO:0006919 IDA:UniProtKBPactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007411 TAS:ReactomePaxon guidance
GO:0008015 TAS:ProtIncPblood circulation
GO:0007155 IEA:UniProtKB-KWPcell adhesion
GO:0008283 IDA:UniProtKBPcell proliferation
GO:0007166 NAS:UniProtKBPcell surface receptor signaling pathway
GO:0030574 TAS:ReactomePcollagen catabolic process
GO:0072577 IDA:UniProtKBPendothelial cell apoptotic process
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0032836 ISS:UniProtKBPglomerular basement membrane development
GO:0016525 IDA:UniProtKBPnegative regulation of angiogenesis
GO:0008285 TAS:ProtIncPnegative regulation of cell proliferation
GO:0010951 NAS:GOCPnegative regulation of endopeptidase activity
GO:0009749 IEA:EnsemblPresponse to glucose
GO:0007605 TAS:ProtIncPsensory perception of sound
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_150268Anchoring fibril formation
REACT_150180Assembly of collagen fibrils and other multimeric structures
REACT_18266Axon guidance
REACT_121139Collagen biosynthesis and modifying enzymes
REACT_150401Collagen degradation
REACT_120729Collagen formation
REACT_118572Degradation of the extracellular matrix
REACT_111045Developmental Biology
REACT_163906ECM proteoglycans
REACT_118779Extracellular matrix organization
REACT_13552Integrin cell surface interactions
REACT_169262Laminin interactions
REACT_18312NCAM1 interactions
REACT_18334NCAM signaling for neurite out-growth
REACT_163874Non-integrin membrane-ECM interactions
REACT_16888Signaling by PDGF
REACT_111102Signal Transduction
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