MGP Database

MGP000661

Record overview

MGPD ID	MGP000661
Gene ID	1359
Species	Homo sapiens (Human)
Gene Name	carboxypeptidase A3 (mast cell)
Gene Symbol	CPA3
Synonyms	MC-CPA;
Alternate names	mast cell carboxypeptidase A; tissue carboxypeptidase A;
Chromosome	3
Map Location	3q24
EC Number	3.4.17.1
Summary	Three different forms of human pancreatic procarboxypeptidase A have been isolated. This gene encodes a form which is obtained as a binary complex of a procarboxypeptidase A with proproteinase E and functions as a secretory granule metalloexopeptidase. [provided by RefSeq, Jan 2009]
Orthologs	View orthologs and multiple alignments for CPA3

Proteins

mast cell carboxypeptidase A precursor

Refseq ID:	NP_001861
Protein GI:	221316749
UniProt ID:	P15088
mRNA ID:	NM_001870
Length:	417
RefSeq Status:

MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEI
EKQFDVKEDIPGRHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATKTYGRN
KIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVY
ITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRE
TMLAVKFIAKYILKHTS

sig_peptide: 1..15
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1582
peptide sequence: 
MRLILPVGLIATTLA

mat_peptide: 16..417
product: mast cell carboxypeptidase A
calculated_mol_wt: 47106
peptide sequence: 
IAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHS
YAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYIL
PVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLFPYG
YTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKH
TS