MGP Database

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MGP000672

Ontology/Pathway Information

Entrez Gene ID1374
Gene Namecarnitine palmitoyltransferase 1A (liver)
Gene Symbol CPT1A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031307 ISS:UniProtKBCintegral component of mitochondrial outer membrane
GO:0016020 IDA:UniProtKBCmembrane
GO:0005743 IEA:EnsemblCmitochondrial inner membrane
GO:0005741 TAS:ReactomeCmitochondrial outer membrane
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0004095 IDA:UniProtKBFcarnitine O-palmitoyltransferase activity
GO:0009437 IDA:UniProtKBPcarnitine metabolic process
GO:0006853 TAS:ReactomePcarnitine shuttle
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0071398 IEA:EnsemblPcellular response to fatty acid
GO:0042755 IEA:EnsemblPeating behavior
GO:0030855 IEP:UniProtKBPepithelial cell differentiation
GO:0006635 TAS:ProtIncPfatty acid beta-oxidation
GO:0006006 IEA:EnsemblPglucose metabolic process
GO:0001676 IDA:UniProtKBPlong-chain fatty acid metabolic process
GO:0032000 IEA:EnsemblPpositive regulation of fatty acid beta-oxidation
GO:0051260 IEA:EnsemblPprotein homooligomerization
GO:0050796 IEA:EnsemblPregulation of insulin secretion
GO:0042493 IEA:EnsemblPresponse to drug
GO:0014070 IEA:EnsemblPresponse to organic cyclic compound
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006641 IEA:EnsemblPtriglyceride metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_24941Circadian Clock
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_11082Import of palmitoyl-CoA into the mitochondrial matrix
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_116145PPARA activates gene expression
REACT_19241Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
REACT_118659RORA activates circadian gene expression
REACT_267785Signaling by Retinoic Acid
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00538Carnitine palmitoyl transferase deficiency (I)
SMP00541Carnitine palmitoyl transferase deficiency (II)
SMP00181Ethylmalonic Encephalopathy
SMP00051Fatty acid Metabolism
SMP00185Glutaric Aciduria Type I
SMP00539Long chain acyl-CoA dehydrogenase deficiency (LCAD)
SMP00542Medium chain acyl-coa dehydrogenase deficiency (MCAD)
SMP00482Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids
SMP00235Short Chain Acyl CoA Dehydrogenase Deficiency (SCAD Deficiency)
SMP00545Trifunctional protein deficiency
SMP00540Very-long-chain acyl coa dehydrogenase deficiency (VLCAD)
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