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MGP000740

Record overview

MGPD IDMGP000740
Gene ID1528
SpeciesHomo sapiens (Human)
Gene Namecytochrome b5 type A (microsomal)
Gene Symbol CYB5A
SynonymsCYB5; MCB5;
Alternate namescytochrome b5; type 1 cyt-b5;
Chromosome18
Map Location18q23
SummaryThe protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
OrthologsView orthologs and multiple alignments for CYB5A

Proteins

cytochrome b5 isoform 1
Refseq ID:NP_683725
Protein GI:41281768
UniProt ID:P00167
mRNA ID:NM_148923
Length:134
RefSeq Status:
MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPETLI
TTIDSSSSWWTNWVIPAISAVAVALMYRLYMAED
 
cytochrome b5 isoform 2
Refseq ID:NP_001905
Protein GI:4503183
UniProt ID:P00167
mRNA ID:NM_001914
Length:98
RefSeq Status:
MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPEP
 
cytochrome b5 isoform 3
Refseq ID:NP_001177736
Protein GI:299829246
UniProt ID:P00167
mRNA ID:NM_001190807
Length:124
RefSeq Status:
MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPETLITTIDSSSSWW
TNWVIPAISAVAVALMYRLYMAED
 
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