MGP Database

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MGP000742

Ontology/Pathway Information

Entrez Gene ID1536
Gene Namecytochrome b-245, beta polypeptide
Gene Symbol CYBB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030425 IEA:EnsemblCdendrite
GO:0005794 IEA:EnsemblCGolgi apparatus
GO:0005887 IDA:UniProtKBCintegral component of plasma membrane
GO:0005739 IEA:EnsemblCmitochondrion
GO:0043020 IDA:BHF-UCLCNADPH oxidase complex
GO:0043025 IEA:EnsemblCneuronal cell body
GO:0030670 TAS:ReactomeCphagocytic vesicle membrane
GO:0005791 IEA:EnsemblCrough endoplasmic reticulum
GO:0050660 IMP:BHF-UCLFflavin adenine dinucleotide binding
GO:0020037 IMP:BHF-UCLFheme binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0046982 IPI:BHF-UCLFprotein heterodimerization activity
GO:0016175 TAS:BHF-UCLFsuperoxide-generating NADPH oxidase activity
GO:0005244 IEA:UniProtKB-KWFvoltage-gated ion channel activity
GO:0042590 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474 TAS:ReactomePantigen processing and presentation of peptide antigen via MHC class I
GO:0050665 IEA:EnsemblPhydrogen peroxide biosynthetic process
GO:0006954 ISS:UniProtKBPinflammatory response
GO:0045087 IMP:BHF-UCLPinnate immune response
GO:0051701 TAS:ReactomePinteraction with host
GO:0055114 IDA:BHF-UCLPoxidation-reduction process
GO:0090382 TAS:ReactomePphagosome maturation
GO:0045730 IMP:BHF-UCLPrespiratory burst
GO:0042493 IEA:EnsemblPresponse to drug
GO:0007584 IEA:EnsemblPresponse to nutrient
GO:0042554 IDA:BHF-UCLPsuperoxide anion generation
GO:0006801 IDA:BHF-UCLPsuperoxide metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_111119Antigen processing-Cross presentation
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_111174Cross-presentation of particulate exogenous antigens (phagosomes)
REACT_116125Disease
REACT_6900Immune System
REACT_121237Latent infection of Homo sapiens with Mycobacterium tuberculosis
REACT_121256Phagosomal maturation (early endosomal stage)
REACT_12529Signaling by VEGF
REACT_111102Signal Transduction
REACT_264464VEGFA-VEGFR2 Pathway
SMP Pathway Links
SMP IDDescription
SMP00716Thyroid hormone synthesis
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