MGP Database

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MGP000783

UniProt Annotations

Entry Information
Gene Namediacylglycerol kinase, beta 90kDa
Protein EntryDGKB_HUMAN
UniProt IDQ9Y6T7
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Y6T7-1; Sequence=Displayed; Name=2; IsoId=Q9Y6T7-2; Sequence=VSP_021898, VSP_021899; Note=No experimental confirmation available.;
Catalytic ActivityATP + 1,2-diacyl-sn-glycerol = ADP + 1,2- diacyl-sn-glycerol 3-phosphate.
Enzyme RegulationStimulated by phosphatidylserine. {ECO:0000250}.
FunctionExhibits high phosphorylation activity for long-chain diacylglycerols. {ECO:0000250}.
Sequence CautionSequence=AAS07533.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the eukaryotic diacylglycerol kinase family. {ECO:0000305}.
SimilarityContains 1 DAGKc domain. {ECO:0000255|PROSITE- ProRule:PRU00783}.
SimilarityContains 2 EF-hand domains. {ECO:0000255|PROSITE- ProRule:PRU00448}.
SimilarityContains 2 phorbol-ester/DAG-type zinc fingers. {ECO:0000255|PROSITE-ProRule:PRU00226}.
Subcellular LocationCytoplasm {ECO:0000250}.
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