MGP Database

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MGP000787

Record overview

MGPD IDMGP000787
Gene ID1612
SpeciesHomo sapiens (Human)
Gene Namedeath-associated protein kinase 1
Gene Symbol DAPK1
SynonymsDAPK;
Alternate namesdeath-associated protein kinase 1; DAP kinase 1;
Chromosome9
Map Location9q21.33
EC Number2.7.11.1;
SummaryDeath-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
OrthologsView orthologs and multiple alignments for DAPK1

Proteins

death-associated protein kinase 1
Refseq ID:NP_001275658
Protein GI:570359575
UniProt ID:P53355
mRNA ID:NM_001288729
Length:1430
RefSeq Status:
MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGE
LFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADM
WSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFA
ARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIK
RGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEA
GCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEAN
CNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKDTHRGLFIQQLRPTQNLQPRIKLKLFGHSGSGK
TTLVESLKCGLLRSFFRRRRPRLSSTNSSRFPPSPLASKPTVSVSINNLYPGCENVSVRSRSMMFEPGLTKGMLEVFVAPTHHPHCSADDQSTKAIDIQN
AYLNGVGDFSVWEFSGNPVYFCCYDYFAANDPTSIHVVVFSLEEPYEIQLNQVIFWLSFLKSLVPVEEPIAFGGKLKNPLQVVLVATHADIMNVPRPAGG
EFGYDKDTSLLKEIRNRFGNDLHISNKLFVLDAGASGSKDMKVLRNHLQEIRSQIVSVCPPMTHLCEKIISTLPSWRKLNGPNQLMSLQQFVYDVQDQLN
PLASEEDLRRIAQQLHSTGEINIMQSETVQDVLLLDPRWLCTNVLGKLLSVETPRALHHYRGRYTVEDIQRLVPDSDVEELLQILDAMDICARDLSSGTM
VDVPALIKTDNLHRSWADEEDEVMVYGGVRIVPVEHLTPFPCGIFHKVQVNLCRWIHQQSTEGDADIRLWVNGCKLANRGAELLVLLVNHGQGIEVQVRG
LETEKIKCCLLLDSVCSTIENVMATTLPGLLTVKHYLSPQQLREHHEPVMIYQPRDFFRAQTLKETSLTNTMGGYKESFSSIMCFGCHDVYSQASLGMDI
HASDLNLLTRRKLSRLLDPPDPLGKDWCLLAMNLGLPDLVAKYNTSNGAPKDFLPSPLHALLREWTTYPESTVGTLMSKLRELGRRDAADFLLKASSVFK
INLDGNGQEAYASSCNSGTSYNSISSVVSR
 
death-associated protein kinase 1
Refseq ID:NP_001275659
Protein GI:570359577
UniProt ID:P53355
mRNA ID:NM_001288730
Length:1430
RefSeq Status:
Protein sequence is identical to GI:570359575 (mRNA isoform)
 
death-associated protein kinase 1
Refseq ID:NP_004929
Protein GI:89363047
UniProt ID:P53355
mRNA ID:NM_004938
Length:1430
RefSeq Status:
Protein sequence is identical to GI:570359575 (mRNA isoform)
 
death-associated protein kinase 1
Refseq ID:NP_001275660
Protein GI:570359579
UniProt ID:P53355
mRNA ID:NM_001288731
Length:1430
RefSeq Status:
Protein sequence is identical to GI:570359575 (mRNA isoform)
 
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