MGP Database

MGP000804

Ontology/Pathway Information

Entrez Gene ID	1644
Gene Name	dopa decarboxylase (aromatic L-amino acid decarboxylase)
Gene Symbol	DDC
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0030424	IEA:Ensembl	C	axon
GO:0005829	TAS:Reactome	C	cytosol
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0043025	IEA:Ensembl	C	neuronal cell body
GO:0008021	IEA:Ensembl	C	synaptic vesicle
GO:0016597	IEA:Ensembl	F	amino acid binding
GO:0004058	IDA:UniProtKB	F	aromatic-L-amino-acid decarboxylase activity
GO:0019899	IPI:ParkinsonsUK-UCL	F	enzyme binding
GO:0036468	IDA:ParkinsonsUK-UCL	F	L-dopa decarboxylase activity
GO:0030170	IEA:InterPro	F	pyridoxal phosphate binding
GO:0042423	TAS:Reactome	P	catecholamine biosynthetic process
GO:0006520	IEA:InterPro	P	cellular amino acid metabolic process
GO:0034641	TAS:Reactome	P	cellular nitrogen compound metabolic process
GO:0071312	IEA:Ensembl	P	cellular response to alkaloid
GO:0035690	IEA:Ensembl	P	cellular response to drug
GO:0071363	IEA:Ensembl	P	cellular response to growth factor stimulus
GO:0007623	IEA:Ensembl	P	circadian rhythm
GO:0042416	IEA:UniProtKB-UniPathway	P	dopamine biosynthetic process
GO:0046219	TAS:Reactome	P	indolalkylamine biosynthetic process
GO:0033076	IEA:Ensembl	P	isoquinoline alkaloid metabolic process
GO:0010259	IEA:Ensembl	P	multicellular organismal aging
GO:0052314	IEA:Ensembl	P	phytoalexin metabolic process
GO:0046684	IEA:Ensembl	P	response to pyrethroid
GO:0042427	IEA:Ensembl	P	serotonin biosynthetic process
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0015842	IEA:Ensembl	P	synaptic vesicle amine transport

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_15513	Amine-derived hormones
REACT_15551	Catecholamine biosynthesis
REACT_111217	Metabolism
REACT_13	Metabolism of amino acids and derivatives
REACT_15439	Serotonin and melatonin biosynthesis

SMP Pathway Links

SMP ID	Description
SMP00169	Alkaptonuria
SMP00170	Aromatic L-Aminoacid Decarboxylase Deficiency
SMP00012	Catecholamine Biosynthesis
SMP00429	Disulfiram Action Pathway
SMP00498	Dopamine beta-hydroxylase deficiency
SMP00190	Hawkinsinuria
SMP00533	Monoamine oxidase-a deficiency (MAO-A)
SMP00063	Tryptophan Metabolism
SMP00497	Tyrosine hydroxylase deficiency
SMP00006	Tyrosine Metabolism
SMP00494	Tyrosinemia, transient, of the newborn
SMP00218	Tyrosinemia Type I