MGP Database

MGP000806

Ontology/Pathway Information

Entrez Gene ID	1646
Gene Name	aldo-keto reductase family 1, member C2
Gene Symbol	AKR1C2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IEA:UniProtKB-SubCell	C	cytoplasm
GO:0004032	IDA:UniProtKB	F	alditol:NADP+ 1-oxidoreductase activity
GO:0032052	IDA:UniProtKB	F	bile acid binding
GO:0031406	IDA:UniProtKB	F	carboxylic acid binding
GO:0047086	IDA:UniProtKB	F	ketosteroid monooxygenase activity
GO:0016655	IDA:UniProtKB	F	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0018636	IDA:UniProtKB	F	phenanthrene 9,10-monooxygenase activity
GO:0047115	IDA:UniProtKB	F	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
GO:0071395	IDA:UniProtKB	P	cellular response to jasmonic acid stimulus
GO:0071799	IDA:UniProtKB	P	cellular response to prostaglandin D stimulus
GO:0044597	IMP:UniProtKB	P	daunorubicin metabolic process
GO:0007586	IDA:UniProtKB	P	digestion
GO:0044598	IMP:UniProtKB	P	doxorubicin metabolic process
GO:0030855	IEP:UniProtKB	P	epithelial cell differentiation
GO:0007186	IDA:UniProtKB	P	G-protein coupled receptor signaling pathway
GO:0055114	IDA:UniProtKB	P	oxidation-reduction process
GO:0008284	IDA:UniProtKB	P	positive regulation of cell proliferation
GO:0051897	IDA:UniProtKB	P	positive regulation of protein kinase B signaling
GO:0042448	IDA:UniProtKB	P	progesterone metabolic process
GO:0006693	IDA:UniProtKB	P	prostaglandin metabolic process
GO:0008202	IDA:UniProtKB	P	steroid metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_11040	Bile acid and bile salt metabolism
REACT_111217	Metabolism
REACT_22258	Metabolism of lipids and lipoproteins
REACT_11054	Synthesis of bile acids and bile salts
REACT_11053	Synthesis of bile acids and bile salts via 24-hydroxycholesterol
REACT_11048	Synthesis of bile acids and bile salts via 27-hydroxycholesterol
REACT_11041	Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol