MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP000827

Ontology/Pathway Information

Entrez Gene ID1718
Gene Name24-dehydrocholesterol reductase
Gene Symbol DHCR24
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005856 IEA:EnsemblCcytoskeleton
GO:0005829 IEA:EnsemblCcytosol
GO:0005783 IDA:UniProtKBCendoplasmic reticulum
GO:0005789 NAS:UniProtKBCendoplasmic reticulum membrane
GO:0000139 IEA:UniProtKB-SubCellCGolgi membrane
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0016020 IDA:UniProtKBCmembrane
GO:0005634 IDA:UniProtKBCnucleus
GO:0000246 IMP:UniProtKBFdelta24(24-1) sterol reductase activity
GO:0050614 IEA:UniProtKB-ECFdelta24-sterol reductase activity
GO:0019899 IPI:UniProtKBFenzyme binding
GO:0050660 IEA:InterProFflavin adenine dinucleotide binding
GO:0016628 IDA:MGIFoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0042605 IPI:UniProtKBFpeptide antigen binding
GO:0008762 IEA:InterProFUDP-N-acetylmuramate dehydrogenase activity
GO:0042987 IEA:EnsemblPamyloid precursor protein catabolic process
GO:0006915 NAS:UniProtKBPapoptotic process
GO:0007050 NAS:UniProtKBPcell cycle arrest
GO:0006695 ISS:UniProtKBPcholesterol biosynthetic process
GO:0030539 IEA:EnsemblPmale genitalia development
GO:0061024 IEA:EnsemblPmembrane organization
GO:0043066 IDA:UniProtKBPnegative regulation of apoptotic process
GO:0008285 IEA:EnsemblPnegative regulation of cell proliferation
GO:0043154 IDA:UniProtKBPnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0055114 IMP:UniProtKBPoxidation-reduction process
GO:0031639 IEA:EnsemblPplasminogen activation
GO:0008104 IEA:EnsemblPprotein localization
GO:0007265 IEA:EnsemblPRas protein signal transduction
GO:1901214 NAS:UniProtKBPregulation of neuron death
GO:0009725 IEA:EnsemblPresponse to hormone
GO:0006979 IEP:UniProtKBPresponse to oxidative stress
GO:0043588 ISS:UniProtKBPskin development
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0009888 IMP:UniProtKBPtissue development
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_9405Cholesterol biosynthesis
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
SMP Pathway Links
SMP IDDescription
SMP00095Alendronate Action Pathway
SMP00131Atorvastatin Action Pathway
SMP00111Cerivastatin Action Pathway
SMP00387CHILD Syndrome
SMP00508Cholesteryl ester storage disease
SMP00388Chondrodysplasia Punctata II, X Linked Dominant (CDPX2)
SMP00386Desmosterolosis
SMP00119Fluvastatin Action Pathway
SMP00209Hypercholesterolemia
SMP00509Hyper-IgD syndrome
SMP00079Ibandronate Action Pathway
SMP00099Lovastatin Action Pathway
SMP00319Lysosomal Acid Lipase Deficiency (Wolman Disease)
SMP00510Mevalonic aciduria
SMP00117Pamidronate Action Pathway
SMP00089Pravastatin Action Pathway
SMP00112Risedronate Action Pathway
SMP00092Rosuvastatin Action Pathway
SMP00082Simvastatin Action Pathway
SMP00389Smith-Lemli-Opitz Syndrome (SLOS)
SMP00023Steroid Biosynthesis
SMP00511Wolman disease
SMP00107Zoledronate Action Pathway
  logo