MGP Database

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MGP000838

Ontology/Pathway Information

Entrez Gene ID1738
Gene Namedihydrolipoamide dehydrogenase
Gene Symbol DLD
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0043159 IEA:EnsemblCacrosomal matrix
GO:0005929 IEA:EnsemblCcilium
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0005654 IDA:HPACnucleoplasm
GO:0004148 TAS:ProtIncFdihydrolipoyl dehydrogenase activity
GO:0050660 IEA:InterProFflavin adenine dinucleotide binding
GO:0009083 TAS:ReactomePbranched-chain amino acid catabolic process
GO:0045454 IEA:InterProPcell redox homeostasis
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0034641 TAS:ReactomePcellular nitrogen compound metabolic process
GO:0007369 IEA:EnsemblPgastrulation
GO:0006554 TAS:ReactomePlysine catabolic process
GO:0006120 IEA:EnsemblPmitochondrial electron transport, NADH to ubiquinone
GO:0006508 IEA:EnsemblPproteolysis
GO:0006090 TAS:ReactomePpyruvate metabolic process
GO:0010510 TAS:ReactomePregulation of acetyl-CoA biosynthetic process from pyruvate
GO:0042391 IEA:EnsemblPregulation of membrane potential
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0048240 IEA:EnsemblPsperm capacitation
GO:0006099 TAS:ReactomePtricarboxylic acid cycle
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_197Branched-chain amino acid catabolism
REACT_1785Citric acid cycle (TCA cycle)
REACT_1298Lysine catabolism
REACT_111217Metabolism
REACT_13Metabolism of amino acids and derivatives
REACT_2071Pyruvate metabolism
REACT_1046Pyruvate metabolism and Citric Acid (TCA) cycle
REACT_12528Regulation of pyruvate dehydrogenase (PDH) complex
REACT_267785Signaling by Retinoic Acid
REACT_111102Signal Transduction
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
SMP Pathway Links
SMP IDDescription
SMP007192-aminoadipic 2-oxoadipic aciduria
SMP005492-ketoglutarate dehydrogenase complex deficiency
SMP001372-Methyl-3-Hydroxybutryl CoA Dehydrogenase Deficiency
SMP001383-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency
SMP005213-hydroxyisobutyric acid dehydrogenase deficiency
SMP005223-hydroxyisobutyric aciduria
SMP002373-Methylcrotonyl Coa Carboxylase Deficiency Type I
SMP001393-Methylglutaconic Aciduria Type I
SMP001403-Methylglutaconic Aciduria Type III
SMP001413-Methylglutaconic Aciduria Type IV
SMP007213-Phosphoglycerate dehydrogenase deficiency
SMP00009Ammonia Recycling
SMP00173Beta-Ketothiolase Deficiency
SMP00057Citric Acid Cycle
SMP00546Congenital lactic acidosis
SMP00179Dihydropyrimidine Dehydrogenase Deficiency (DHPD)
SMP00242Dimethylglycine Dehydrogenase Deficiency
SMP00484Dimethylglycinuria
SMP00547Fumarase deficiency
SMP00186Glutaric Aciduria Type III
SMP00004Glycine and Serine Metabolism
SMP00485Hyperglycinemia, non-ketotic
SMP00527Hyperlysinemia I, Familial
SMP00528Hyperlysinemia II or Saccharopinuria
SMP00523Isobutyryl-coa dehydrogenase deficiency
SMP00524Isovaleric acidemia
SMP00238Isovaleric Aciduria
SMP00196Leigh Syndrome
SMP00037Lysine Degradation
SMP00199Maple Syrup Urine Disease
SMP00384Methylmalonate Semialdehyde Dehydrogenase Deficiency
SMP00200Methylmalonic Aciduria
SMP00548Mitochondrial complex II deficiency
SMP00223Non Ketotic Hyperglycinemia
SMP00558Primary hyperoxaluria II, PH2
SMP00236Propionic Acidemia
SMP00571Pyridoxine dependency with seizures
SMP00334Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)
SMP00212Pyruvate Dehydrogenase Complex Deficiency
SMP00551Pyruvate dehydrogenase deficiency (E2)
SMP00550Pyruvate dehydrogenase deficiency (E3)
SMP00559Pyruvate kinase deficiency
SMP00060Pyruvate Metabolism
SMP00239Saccharopinuria/Hyperlysinemia II
SMP00244Sarcosinemia
SMP00452Threonine and 2-Oxobutanoate Degradation
SMP00032Valine, Leucine and Isoleucine Degradation
SMP00654Warburg Effect
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