MGP Database

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MGP000842

Ontology/Pathway Information

Entrez Gene ID1743
Gene Namedihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
Gene Symbol DLST
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005634 IDA:UniProtKBCnucleus
GO:0045252 IEA:InterProCoxoglutarate dehydrogenase complex
GO:0004149 IEA:UniProtKB-ECFdihydrolipoyllysine-residue succinyltransferase activity
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0034641 TAS:ReactomePcellular nitrogen compound metabolic process
GO:0006091 TAS:ProtIncPgeneration of precursor metabolites and energy
GO:0033512 IEA:UniProtKB-UniPathwayPL-lysine catabolic process to acetyl-CoA via saccharopine
GO:0006554 TAS:ReactomePlysine catabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006099 TAS:ReactomePtricarboxylic acid cycle
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1785Citric acid cycle (TCA cycle)
REACT_1298Lysine catabolism
REACT_111217Metabolism
REACT_13Metabolism of amino acids and derivatives
REACT_1046Pyruvate metabolism and Citric Acid (TCA) cycle
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
SMP Pathway Links
SMP IDDescription
SMP007192-aminoadipic 2-oxoadipic aciduria
SMP005492-ketoglutarate dehydrogenase complex deficiency
SMP00057Citric Acid Cycle
SMP00546Congenital lactic acidosis
SMP00547Fumarase deficiency
SMP00186Glutaric Aciduria Type III
SMP00527Hyperlysinemia I, Familial
SMP00528Hyperlysinemia II or Saccharopinuria
SMP00037Lysine Degradation
SMP00548Mitochondrial complex II deficiency
SMP00571Pyridoxine dependency with seizures
SMP00551Pyruvate dehydrogenase deficiency (E2)
SMP00550Pyruvate dehydrogenase deficiency (E3)
SMP00239Saccharopinuria/Hyperlysinemia II
SMP00654Warburg Effect
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