MGP Database

MGP000864

Ontology/Pathway Information

Entrez Gene ID1803
Gene Namedipeptidyl-peptidase 4
Gene Symbol DPP4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016324 IDA:UniProtKBCapical plasma membrane
GO:0009986 IDA:UniProtKBCcell surface
GO:0030139 IDA:UniProtKBCendocytic vesicle
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0046581 IEA:EnsemblCintercellular canaliculus
GO:0071438 IDA:UniProtKBCinvadopodium membrane
GO:0030027 IDA:UniProtKBClamellipodium
GO:0031258 IEA:UniProtKB-SubCellClamellipodium membrane
GO:0005765 IDA:UniProtKBClysosomal membrane
GO:0016020 IDA:UniProtKBCmembrane
GO:0045121 IEA:UniProtKB-SubCellCmembrane raft
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0008239 IDA:UniProtKBFdipeptidyl-peptidase activity
GO:0042802 IPI:IntActFidentical protein binding
GO:0002020 IPI:UniProtKBFprotease binding
GO:0042803 IPI:UniProtKBFprotein homodimerization activity
GO:0005102 IPI:UniProtKBFreceptor binding
GO:0004252 IEA:InterProFserine-type endopeptidase activity
GO:0008236 IDA:UniProtKBFserine-type peptidase activity
GO:0007155 IEA:UniProtKB-KWPcell adhesion
GO:0043542 IDA:UniProtKBPendothelial cell migration
GO:0010716 IDA:UniProtKBPnegative regulation of extracellular matrix disassembly
GO:0008284 IDA:UniProtKBPpositive regulation of cell proliferation
GO:0033632 IDA:UniProtKBPregulation of cell-cell adhesion mediated by integrin
GO:0001666 IDA:UniProtKBPresponse to hypoxia
GO:0042110 IDA:UniProtKBPT cell activation
GO:0031295 IDA:UniProtKBPT cell costimulation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_23974Incretin synthesis, secretion, and inactivation
REACT_17015Metabolism of proteins
REACT_160078Peptide hormone metabolism
REACT_24019Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
REACT_23824Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
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