MGP Database

MGP000881

Ontology/Pathway Information

Entrez Gene ID	1832
Gene Name	desmoplakin
Gene Symbol	DSP
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0016323	IEA:Ensembl	C	basolateral plasma membrane
GO:0001533	IDA:UniProtKB	C	cornified envelope
GO:0030057	IEA:UniProtKB-SubCell	C	desmosome
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005916	IEA:Ensembl	C	fascia adherens
GO:0014704	IDA:BHF-UCL	C	intercalated disc
GO:0005882	IEA:Ensembl	C	intermediate filament
GO:0005739	IEA:Ensembl	C	mitochondrion
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0005886	IDA:UniProtKB	C	plasma membrane
GO:0044822	IDA:UniProtKB	F	poly(A) RNA binding
GO:0030674	IDA:UniProtKB	F	protein binding, bridging
GO:0005080	IPI:BHF-UCL	F	protein kinase C binding
GO:0097110	IPI:BHF-UCL	F	scaffold protein binding
GO:0005200	TAS:ProtInc	F	structural constituent of cytoskeleton
GO:0005198	IDA:UniProtKB	F	structural molecule activity
GO:0034332	IEA:Ensembl	P	adherens junction organization
GO:0006915	TAS:Reactome	P	apoptotic process
GO:0086069	IMP:BHF-UCL	P	bundle of His cell to Purkinje myocyte communication
GO:0006921	TAS:Reactome	P	cellular component disassembly involved in execution phase of apoptosis
GO:0002934	ISS:BHF-UCL	P	desmosome organization
GO:0008544	TAS:ProtInc	P	epidermis development
GO:0045109	ISS:BHF-UCL	P	intermediate filament organization
GO:0030216	IDA:UniProtKB	P	keratinocyte differentiation
GO:0018149	IDA:UniProtKB	P	peptide cross-linking
GO:0071896	ISS:BHF-UCL	P	protein localization to adherens junction
GO:0086091	IMP:BHF-UCL	P	regulation of heart rate by cardiac conduction
GO:0016337	IEA:Ensembl	P	single organismal cell-cell adhesion
GO:0086005	IMP:BHF-UCL	P	ventricular cardiac muscle cell action potential
GO:0003223	ISS:BHF-UCL	P	ventricular compact myocardium morphogenesis
GO:0042060	IEA:Ensembl	P	wound healing

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_578	Apoptosis
REACT_13579	Apoptotic cleavage of cell adhesion proteins
REACT_107	Apoptotic cleavage of cellular proteins
REACT_995	Apoptotic execution phase
REACT_268456	Programmed Cell Death