MGP Database

MGP000881

Ontology/Pathway Information

Entrez Gene ID1832
Gene Namedesmoplakin
Gene Symbol DSP
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016323 IEA:EnsemblCbasolateral plasma membrane
GO:0001533 IDA:UniProtKBCcornified envelope
GO:0030057 IEA:UniProtKB-SubCellCdesmosome
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005916 IEA:EnsemblCfascia adherens
GO:0014704 IDA:BHF-UCLCintercalated disc
GO:0005882 IEA:EnsemblCintermediate filament
GO:0005739 IEA:EnsemblCmitochondrion
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0030674 IDA:UniProtKBFprotein binding, bridging
GO:0005080 IPI:BHF-UCLFprotein kinase C binding
GO:0097110 IPI:BHF-UCLFscaffold protein binding
GO:0005200 TAS:ProtIncFstructural constituent of cytoskeleton
GO:0005198 IDA:UniProtKBFstructural molecule activity
GO:0034332 IEA:EnsemblPadherens junction organization
GO:0006915 TAS:ReactomePapoptotic process
GO:0086069 IMP:BHF-UCLPbundle of His cell to Purkinje myocyte communication
GO:0006921 TAS:ReactomePcellular component disassembly involved in execution phase of apoptosis
GO:0002934 ISS:BHF-UCLPdesmosome organization
GO:0008544 TAS:ProtIncPepidermis development
GO:0045109 ISS:BHF-UCLPintermediate filament organization
GO:0030216 IDA:UniProtKBPkeratinocyte differentiation
GO:0018149 IDA:UniProtKBPpeptide cross-linking
GO:0071896 ISS:BHF-UCLPprotein localization to adherens junction
GO:0086091 IMP:BHF-UCLPregulation of heart rate by cardiac conduction
GO:0016337 IEA:EnsemblPsingle organismal cell-cell adhesion
GO:0086005 IMP:BHF-UCLPventricular cardiac muscle cell action potential
GO:0003223 ISS:BHF-UCLPventricular compact myocardium morphogenesis
GO:0042060 IEA:EnsemblPwound healing
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_578Apoptosis
REACT_13579Apoptotic cleavage of cell adhesion proteins
REACT_107Apoptotic cleavage of cellular proteins
REACT_995Apoptotic execution phase
REACT_268456Programmed Cell Death
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