MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP000915

UniProt Annotations

Entry Information
Gene Nameeukaryotic translation elongation factor 1 beta 2
Protein EntryEF1B_HUMAN
UniProt IDP24534
SpeciesHuman
Comments
Comment typeDescription
FunctionEF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
InductionBy homocysteine (HC), may mediate accelerated synthesis of free thiol-containing proteins in response to HC-induced oxidative stress. {ECO:0000269|PubMed:9677419}.
InteractionP26641:EEF1G; NbExp=3; IntAct=EBI-354334, EBI-351467;
PtmPhosphorylation affects the GDP/GTP exchange rate. {ECO:0000269|PubMed:17081983, ECO:0000269|PubMed:17487921, ECO:0000269|PubMed:17693683, ECO:0000269|PubMed:18318008, ECO:0000269|PubMed:18669648, ECO:0000269|PubMed:18691976, ECO:0000269|PubMed:19369195, ECO:0000269|PubMed:19690332, ECO:0000269|PubMed:20068231, ECO:0000269|PubMed:21406692}.
SimilarityBelongs to the EF-1-beta/EF-1-delta family. {ECO:0000305}.
SimilarityContains 1 GST C-terminal domain. {ECO:0000305}.
SubunitEF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
  logo