MGP Database

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MGP000936

Ontology/Pathway Information

Entrez Gene ID1969
Gene NameEPH receptor A2
Gene Symbol EPHA2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:UniProtKBCcell surface
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0005887 IDA:UniProtKBCintegral component of plasma membrane
GO:0031258 IEA:UniProtKB-SubCellClamellipodium membrane
GO:0031256 IDA:UniProtKBCleading edge membrane
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0032587 IEA:UniProtKB-SubCellCruffle membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0005003 IEA:InterProFephrin receptor activity
GO:0004714 IDA:UniProtKBFtransmembrane receptor protein tyrosine kinase activity
GO:0032863 IMP:UniProtKBPactivation of Rac GTPase activity
GO:0001525 IEA:UniProtKB-KWPangiogenesis
GO:0048320 IEA:EnsemblPaxial mesoderm formation
GO:0046849 ISS:UniProtKBPbone remodeling
GO:0060444 ISS:UniProtKBPbranching involved in mammary gland duct morphogenesis
GO:0007155 IEA:UniProtKB-KWPcell adhesion
GO:0060326 IMP:UniProtKBPcell chemotaxis
GO:0016477 IMP:UniProtKBPcell migration
GO:0048013 IDA:UniProtKBPephrin receptor signaling pathway
GO:0008630 IDA:UniProtKBPintrinsic apoptotic signaling pathway in response to DNA damage
GO:0030216 IMP:UniProtKBPkeratinocyte differentiation
GO:0070309 ISS:UniProtKBPlens fiber cell morphogenesis
GO:0033598 ISS:UniProtKBPmammary gland epithelial cell proliferation
GO:0007275 TAS:ProtIncPmulticellular organismal development
GO:0051898 IDA:UniProtKBPnegative regulation of protein kinase B signaling
GO:0021915 IEA:EnsemblPneural tube development
GO:0030182 IEA:EnsemblPneuron differentiation
GO:0060035 IEA:EnsemblPnotochord cell development
GO:0014028 IEA:EnsemblPnotochord formation
GO:0001649 ISS:UniProtKBPosteoblast differentiation
GO:0030316 ISS:UniProtKBPosteoclast differentiation
GO:0018108 IDA:GOCPpeptidyl-tyrosine phosphorylation
GO:0090004 IMP:UniProtKBPpositive regulation of establishment of protein localization to plasma membrane
GO:0036342 IEA:EnsemblPpost-anal tail morphogenesis
GO:0043491 IDA:UniProtKBPprotein kinase B signaling
GO:0045765 ISS:UniProtKBPregulation of angiogenesis
GO:0043535 ISS:UniProtKBPregulation of blood vessel endothelial cell migration
GO:0033628 IDA:UniProtKBPregulation of cell adhesion mediated by integrin
GO:0070372 IMP:UniProtKBPregulation of ERK1 and ERK2 cascade
GO:0010591 IMP:UniProtKBPregulation of lamellipodium assembly
GO:0070848 IMP:UniProtKBPresponse to growth factor
GO:0001501 IEA:EnsemblPskeletal system development
GO:0001570 IEA:EnsemblPvasculogenesis
GO:0016032 IEA:UniProtKB-KWPviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_111045Developmental Biology
REACT_264548EPHA-mediated growth cone collapse
REACT_264198EPH-ephrin mediated repulsion of cells
REACT_264068EPH-Ephrin signaling
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