MGP Database

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MGP000963

Ontology/Pathway Information

Entrez Gene ID2043
Gene NameEPH receptor A4
Gene Symbol EPHA4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030424 ISS:UniProtKBCaxon
GO:0044295 IEA:EnsemblCaxonal growth cone
GO:0043679 IEA:EnsemblCaxon terminus
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0009986 IEA:EnsemblCcell surface
GO:0005737 ISS:UniProtKBCcytoplasm
GO:0030425 ISS:UniProtKBCdendrite
GO:0043197 IEA:EnsemblCdendritic spine
GO:0031901 ISS:UniProtKBCearly endosome membrane
GO:0005783 IEA:EnsemblCendoplasmic reticulum
GO:0030175 IEA:EnsemblCfilopodium
GO:0005794 IEA:EnsemblCGolgi apparatus
GO:0005887 ISS:UniProtKBCintegral component of plasma membrane
GO:0005741 IEA:EnsemblCmitochondrial outer membrane
GO:0031594 IEA:EnsemblCneuromuscular junction
GO:0043204 IEA:EnsemblCperikaryon
GO:0014069 IEA:UniProtKB-SubCellCpostsynaptic density
GO:0045211 IEA:UniProtKB-KWCpostsynaptic membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0097161 IDA:UniProtKBFDH domain binding
GO:0005004 ISS:UniProtKBFGPI-linked ephrin receptor activity
GO:0042731 IPI:UniProtKBFPH domain binding
GO:0004672 IDA:UniProtKBFprotein kinase activity
GO:0005005 ISS:UniProtKBFtransmembrane-ephrin receptor activity
GO:0007628 IEA:EnsemblPadult walking behavior
GO:0007155 IEA:UniProtKB-KWPcell adhesion
GO:0021957 ISS:UniProtKBPcorticospinal tract morphogenesis
GO:0097156 ISS:UniProtKBPfasciculation of motor neuron axon
GO:0097155 ISS:UniProtKBPfasciculation of sensory neuron axon
GO:0008347 IEA:EnsemblPglial cell migration
GO:0008045 ISS:UniProtKBPmotor neuron axon guidance
GO:0048681 ISS:UniProtKBPnegative regulation of axon regeneration
GO:0018108 IDA:UniProtKBPpeptidyl-tyrosine phosphorylation
GO:0050775 IEA:EnsemblPpositive regulation of dendrite morphogenesis
GO:0043507 IEA:EnsemblPpositive regulation of JUN kinase activity
GO:2001108 IDA:UniProtKBPpositive regulation of Rho guanyl-nucleotide exchange factor activity
GO:0046777 IDA:UniProtKBPprotein autophosphorylation
GO:0048710 ISS:UniProtKBPregulation of astrocyte differentiation
GO:0050770 ISS:UniProtKBPregulation of axonogenesis
GO:0061001 ISS:UniProtKBPregulation of dendritic spine morphogenesis
GO:0032314 ISS:UniProtKBPregulation of Rac GTPase activity
GO:0032317 ISS:UniProtKBPregulation of Rap GTPase activity
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_111045Developmental Biology
REACT_264548EPHA-mediated growth cone collapse
REACT_264198EPH-ephrin mediated repulsion of cells
REACT_264068EPH-Ephrin signaling
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