MGP Database

MGP000968

Ontology/Pathway Information

Entrez Gene ID	2048
Gene Name	EPH receptor B2
Gene Symbol	EPHB2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0030424	ISS:UniProtKB	C	axon
GO:0030425	ISS:UniProtKB	C	dendrite
GO:0005887	ISS:UniProtKB	C	integral component of plasma membrane
GO:0043025	IEA:Ensembl	C	neuronal cell body
GO:0005524	IEA:UniProtKB-KW	F	ATP binding
GO:0008046	IEA:Ensembl	F	axon guidance receptor activity
GO:0004713	ISS:UniProtKB	F	protein tyrosine kinase activity
GO:0005005	ISS:UniProtKB	F	transmembrane-ephrin receptor activity
GO:0001525	ISS:UniProtKB	P	angiogenesis
GO:0007413	ISS:UniProtKB	P	axonal fasciculation
GO:0007411	ISS:UniProtKB	P	axon guidance
GO:0048593	IEA:Ensembl	P	camera-type eye morphogenesis
GO:0021952	IEA:Ensembl	P	central nervous system projection neuron axonogenesis
GO:0071679	ISS:UniProtKB	P	commissural neuron axon guidance
GO:0022038	ISS:UniProtKB	P	corpus callosum development
GO:0060996	ISS:UniProtKB	P	dendritic spine development
GO:0060997	ISS:UniProtKB	P	dendritic spine morphogenesis
GO:0048013	ISS:UniProtKB	P	ephrin receptor signaling pathway
GO:0042472	ISS:UniProtKB	P	inner ear morphogenesis
GO:0007612	IEA:Ensembl	P	learning
GO:0050771	IEA:Ensembl	P	negative regulation of axonogenesis
GO:0007399	TAS:UniProtKB	P	nervous system development
GO:0021631	IEA:Ensembl	P	optic nerve morphogenesis
GO:0060021	ISS:UniProtKB	P	palate development
GO:0018108	ISS:UniProtKB	P	peptidyl-tyrosine phosphorylation
GO:0016310	ISS:UniProtKB	P	phosphorylation
GO:0048170	IEA:Ensembl	P	positive regulation of long-term neuronal synaptic plasticity
GO:0051965	ISS:UniProtKB	P	positive regulation of synapse assembly
GO:0050878	ISS:UniProtKB	P	regulation of body fluid levels
GO:0031290	IEA:Ensembl	P	retinal ganglion cell axon guidance
GO:0001655	ISS:UniProtKB	P	urogenital system development

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_18266	Axon guidance
REACT_111045	Developmental Biology
REACT_263952	EPHB-mediated forward signaling
REACT_264198	EPH-ephrin mediated repulsion of cells
REACT_264068	EPH-Ephrin signaling
REACT_264047	Ephrin signaling
REACT_22205	L1CAM interactions