MGP Database

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MGP000973

Ontology/Pathway Information

Entrez Gene ID2053
Gene Nameepoxide hydrolase 2, cytoplasmic
Gene Symbol EPHX2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005829 IDA:UniProtKBCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005777 IDA:UniProtKBCperoxisome
GO:0033885 IEA:UniProtKB-ECF10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity
GO:0004301 IDA:UniProtKBFepoxide hydrolase activity
GO:0042577 IDA:UniProtKBFlipid phosphatase activity
GO:0000287 IDA:UniProtKBFmagnesium ion binding
GO:0016791 IDA:UniProtKBFphosphatase activity
GO:0042803 IDA:UniProtKBFprotein homodimerization activity
GO:0005102 IPI:UniProtKBFreceptor binding
GO:0015643 IDA:UniProtKBFtoxic substance binding
GO:0019369 TAS:ReactomeParachidonic acid metabolic process
GO:0006874 NAS:UniProtKBPcellular calcium ion homeostasis
GO:0042632 IDA:UniProtKBPcholesterol homeostasis
GO:0016311 IDA:UniProtKBPdephosphorylation
GO:0017144 NAS:UniProtKBPdrug metabolic process
GO:0019373 TAS:ReactomePepoxygenase P450 pathway
GO:0006954 NAS:UniProtKBPinflammatory response
GO:0046839 IDA:UniProtKBPphospholipid dephosphorylation
GO:0010628 IDA:UniProtKBPpositive regulation of gene expression
GO:0045909 NAS:UniProtKBPpositive regulation of vasodilation
GO:0072593 NAS:UniProtKBPreactive oxygen species metabolic process
GO:0008217 NAS:UniProtKBPregulation of blood pressure
GO:0090181 IMP:UniProtKBPregulation of cholesterol metabolic process
GO:0009636 NAS:UniProtKBPresponse to toxic substance
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0046272 IDA:UniProtKBPstilbene catabolic process
GO:0006805 NAS:UniProtKBPxenobiotic metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147851Arachidonic acid metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_150417Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
SMP Pathway Links
SMP IDDescription
SMP00710Acetaminophen Action Pathway
SMP00083Acetylsalicylic Acid Action Pathway
SMP00692Antipyrine Action Pathway
SMP00693Antrafenine Action Pathway
SMP00075Arachidonic Acid Metabolism
SMP00102Bromfenac Action Pathway
SMP00694Carprofen Action Pathway
SMP00096Celecoxib Action Pathway
SMP00093Diclofenac Action Pathway
SMP00289Diflunisal Action Pathway
SMP00084Etodolac Action Pathway
SMP00695Etoricoxib Action Pathway
SMP00696Fenoprofen Action Pathway
SMP00697Flurbiprofen Action Pathway
SMP00086Ibuprofen Action Pathway
SMP00104Indomethacin Action Pathway
SMP00085Ketoprofen Action Pathway
SMP00098Ketorolac Action Pathway
SMP00353Leukotriene C4 Synthesis Deficiency
SMP00700Lornoxicam Action Pathway
SMP00699Lumiracoxib Action Pathway
SMP00698Magnesium salicylate Action Pathway
SMP00109Mefenamic Acid Action Pathway
SMP00106Meloxicam Action Pathway
SMP00114Nabumetone Action Pathway
SMP00120Naproxen Action Pathway
SMP00702Nepafenac Action Pathway
SMP00113Oxaprozin Action Pathway
SMP00701Phenylbutazone Action Pathway
SMP00077Piroxicam Action Pathway
SMP00087Rofecoxib Action Pathway
SMP00708Salicylate-sodium Action Pathway
SMP00709Salicylic Acid Action Pathway
SMP00707Salsalate Action Pathway
SMP00094Sulindac Action Pathway
SMP00101Suprofen Action Pathway
SMP00706Tenoxicam Action Pathway
SMP00705Tiaprofenic Acid Action Pathway
SMP00704Tolmetin Action Pathway
SMP00703Trisalicylate-choline Action Pathway
SMP00116Valdecoxib Action Pathway
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