MGP Database

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MGP000975

Ontology/Pathway Information

Entrez Gene ID2058
Gene Nameglutamyl-prolyl-tRNA synthetase
Gene Symbol EPRS
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 TAS:ProtIncCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0097452 IDA:UniProtKBCGAIT complex
GO:0016020 IDA:UniProtKBCmembrane
GO:0030529 IDA:UniProtKBCribonucleoprotein complex
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004818 TAS:ReactomeFglutamate-tRNA ligase activity
GO:0004827 TAS:ReactomeFproline-tRNA ligase activity
GO:0035613 IDA:UniProtKBFRNA stem-loop binding
GO:0071346 IDA:UniProtKBPcellular response to interferon-gamma
GO:0010467 TAS:ReactomePgene expression
GO:0006424 IEA:InterProPglutamyl-tRNA aminoacylation
GO:0017148 IDA:UniProtKBPnegative regulation of translation
GO:0006433 IEA:InterProPprolyl-tRNA aminoacylation
GO:0006461 TAS:ProtIncPprotein complex assembly
GO:0006418 TAS:ReactomePtRNA aminoacylation for protein translation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15306Cytosolic tRNA aminoacylation
REACT_71Gene Expression
REACT_15482tRNA Aminoacylation
SMP Pathway Links
SMP IDDescription
SMP00020Arginine and Proline Metabolism
SMP00362Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)
SMP00504Creatine deficiency, guanidinoacetate methyltransferase deficiency
SMP00188Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency)
SMP00506Hyperornithinemia-hyperammonemia-homocitrullinuria [HHH-syndrome]
SMP00505Hyperornithinemia with gyrate atrophy (HOGA)
SMP00361Hyperprolinemia Type I
SMP00360Hyperprolinemia Type II
SMP00507L-arginine:glycine amidinotransferase deficiency
SMP00363Ornithine Aminotransferase Deficiency (OAT Deficiency)
SMP00207Prolidase Deficiency (PD)
SMP00208Prolinemia Type II
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