MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP000980

Ontology/Pathway Information

Entrez Gene ID2068
Gene Nameexcision repair cross-complementation group 2
Gene Symbol ERCC2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0000439 IEA:EnsemblCcore TFIIH complex
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005675 IDA:UniProtKBCholo TFIIH complex
GO:0071817 IDA:UniProtKBCMMXD complex
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0005819 IDA:UniProtKBCspindle
GO:0051539 IEA:UniProtKB-KWF4 iron, 4 sulfur cluster binding
GO:0043139 IDA:UniProtKBF5'-3' DNA helicase activity
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004003 IEA:InterProFATP-dependent DNA helicase activity
GO:0003677 IEA:UniProtKB-KWFDNA binding
GO:0008094 TAS:UniProtKBFDNA-dependent ATPase activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0008022 IPI:UniProtKBFprotein C-terminus binding
GO:0047485 IPI:UniProtKBFprotein N-terminus binding
GO:0006370 TAS:ReactomeP7-methylguanosine mRNA capping
GO:0007568 IEA:EnsemblPaging
GO:0006915 IMP:UniProtKBPapoptotic process
GO:0006200 IDA:GOCPATP catabolic process
GO:0030282 IEA:EnsemblPbone mineralization
GO:0008283 IEA:EnsemblPcell proliferation
GO:0032289 IEA:EnsemblPcentral nervous system myelin formation
GO:0007059 IMP:UniProtKBPchromosome segregation
GO:0032508 IDA:GOCPDNA duplex unwinding
GO:0006281 TAS:ReactomePDNA repair
GO:0040016 IEA:EnsemblPembryonic cleavage
GO:0043249 IEA:EnsemblPerythrocyte maturation
GO:0030198 IEA:EnsemblPextracellular matrix organization
GO:0010467 TAS:ReactomePgene expression
GO:0035315 IMP:UniProtKBPhair cell differentiation
GO:0048820 IEA:EnsemblPhair follicle maturation
GO:0060218 IEA:EnsemblPhematopoietic stem cell differentiation
GO:0001701 IEA:EnsemblPin utero embryonic development
GO:0035264 IEA:EnsemblPmulticellular organism growth
GO:0006289 NAS:UniProtKBPnucleotide-excision repair
GO:0000718 TAS:ReactomePnucleotide-excision repair, DNA damage removal
GO:0033683 IMP:UniProtKBPnucleotide-excision repair, DNA incision
GO:0043388 IEA:EnsemblPpositive regulation of DNA binding
GO:0045893 IDA:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0045944 IDA:UniProtKBPpositive regulation of transcription from RNA polymerase II promoter
GO:0050434 TAS:ReactomePpositive regulation of viral transcription
GO:0009791 IEA:EnsemblPpost-embryonic development
GO:0006468 IDA:GOCPprotein phosphorylation
GO:1901990 IMP:UniProtKBPregulation of mitotic cell cycle phase transition
GO:0001666 IEA:EnsemblPresponse to hypoxia
GO:0006979 IMP:UniProtKBPresponse to oxidative stress
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0021510 IEA:EnsemblPspinal cord development
GO:0006363 TAS:ReactomePtermination of RNA polymerase I transcription
GO:0006283 IDA:UniProtKBPtranscription-coupled nucleotide-excision repair
GO:0006368 TAS:ReactomePtranscription elongation from RNA polymerase II promoter
GO:0006362 TAS:ReactomePtranscription elongation from RNA polymerase I promoter
GO:0006366 IDA:UniProtKBPtranscription from RNA polymerase II promoter
GO:0006360 TAS:ReactomePtranscription from RNA polymerase I promoter
GO:0006367 TAS:ReactomePtranscription initiation from RNA polymerase II promoter
GO:0006361 TAS:ReactomePtranscription initiation from RNA polymerase I promoter
GO:0009650 IGI:MGIPUV protection
GO:0016032 TAS:ReactomePviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_160176Cytosolic iron-sulfur cluster assembly
REACT_116125Disease
REACT_216DNA Repair
REACT_311Dual incision reaction in GG-NER
REACT_2222Dual incision reaction in TC-NER
REACT_264098Epigenetic regulation of gene expression
REACT_6346Formation of HIV-1 elongation complex containing HIV-1 Tat
REACT_22201Formation of HIV elongation complex in the absence of HIV Tat
REACT_257Formation of incision complex in GG-NER
REACT_1845Formation of RNA Pol II elongation complex
REACT_846Formation of the Early Elongation Complex
REACT_6319Formation of the HIV-1 Early Elongation Complex
REACT_1941Formation of transcription-coupled NER (TC-NER) repair complex
REACT_71Gene Expression
REACT_2253Global Genomic NER (GG-NER)
REACT_6185HIV Infection
REACT_6256HIV Life Cycle
REACT_6274HIV Transcription Elongation
REACT_6332HIV Transcription Initiation
REACT_6361Late Phase of HIV Life Cycle
REACT_111217Metabolism
REACT_1470mRNA Capping
REACT_264000Negative epigenetic regulation of rRNA expression
REACT_263965NoRC negatively regulates rRNA expression
REACT_1826Nucleotide Excision Repair
REACT_6237RNA Pol II CTD phosphorylation and interaction with CE
REACT_975RNA Pol II CTD phosphorylation and interaction with CE
REACT_2204RNA Polymerase I Chain Elongation
REACT_6253RNA Polymerase II HIV Promoter Escape
REACT_22107RNA Polymerase II Pre-transcription Events
REACT_2089RNA Polymerase II Promoter Escape
REACT_1366RNA Polymerase II Transcription
REACT_833RNA Polymerase II Transcription Elongation
REACT_1851RNA Polymerase II Transcription Initiation
REACT_834RNA Polymerase II Transcription Initiation And Promoter Clearance
REACT_1655RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
REACT_1974RNA Polymerase I Promoter Clearance
REACT_1913RNA Polymerase I Promoter Escape
REACT_21352RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
REACT_1309RNA Polymerase I Transcription
REACT_953RNA Polymerase I Transcription Initiation
REACT_1074RNA Polymerase I Transcription Termination
REACT_6162Tat-mediated elongation of the HIV-1 transcript
REACT_1628Transcription-coupled NER (TC-NER)
REACT_6233Transcription of the HIV genome
SMP Pathway Links
SMP IDDescription
SMP00478Nucleotide Excision Repair
  logo