MGP Database

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MGP000983

Ontology/Pathway Information

Entrez Gene ID2072
Gene Nameexcision repair cross-complementation group 4
Gene Symbol ERCC4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0000781 IDA:BHF-UCLCchromosome, telomeric region
GO:0000784 IDA:UniProtKBCnuclear chromosome, telomeric region
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0000109 IDA:MGICnucleotide-excision repair complex
GO:0000110 IDA:UniProtKBCnucleotide-excision repair factor 1 complex
GO:0005634 IDA:UniProtKBCnucleus
GO:0005669 IEA:EnsemblCtranscription factor TFIID complex
GO:0003684 IMP:UniProtKBFdamaged DNA binding
GO:0004520 IDA:UniProtKBFendodeoxyribonuclease activity
GO:0008022 IPI:UniProtKBFprotein C-terminus binding
GO:0047485 IPI:UniProtKBFprotein N-terminus binding
GO:0003697 IDA:UniProtKBFsingle-stranded DNA binding
GO:0000014 IBA:GO_CentralFsingle-stranded DNA endodeoxyribonuclease activity
GO:0000737 IDA:GOCPDNA catabolic process, endonucleolytic
GO:0006281 IMP:UniProtKBPDNA repair
GO:0000724 IMP:UniProtKBPdouble-strand break repair via homologous recombination
GO:0032205 IMP:UniProtKBPnegative regulation of telomere maintenance
GO:0006289 IMP:UniProtKBPnucleotide-excision repair
GO:0000718 TAS:ReactomePnucleotide-excision repair, DNA damage removal
GO:0033683 IDA:UniProtKBPnucleotide-excision repair, DNA incision
GO:0006295 IMP:UniProtKBPnucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 IMP:UniProtKBPnucleotide-excision repair, DNA incision, 5'-to lesion
GO:1901255 IBA:GO_CentralPnucleotide-excision repair involved in interstrand cross-link repair
GO:0000712 IBA:GO_CentralPresolution of meiotic recombination intermediates
GO:0009411 IMP:UniProtKBPresponse to UV
GO:0000723 IMP:BHF-UCLPtelomere maintenance
GO:0010834 IMP:BHF-UCLPtelomere maintenance via telomere shortening
GO:0006283 TAS:ReactomePtranscription-coupled nucleotide-excision repair
GO:0009650 IEA:EnsemblPUV protection
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_216DNA Repair
REACT_311Dual incision reaction in GG-NER
REACT_2222Dual incision reaction in TC-NER
REACT_257Formation of incision complex in GG-NER
REACT_1941Formation of transcription-coupled NER (TC-NER) repair complex
REACT_2253Global Genomic NER (GG-NER)
REACT_1826Nucleotide Excision Repair
REACT_1628Transcription-coupled NER (TC-NER)
SMP Pathway Links
SMP IDDescription
SMP00478Nucleotide Excision Repair
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