MGP Database

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MGP000984

Ontology/Pathway Information

Entrez Gene ID2073
Gene Nameexcision repair cross-complementation group 5
Gene Symbol ERCC5
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0045111 IDA:HPACintermediate filament cytoskeleton
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0000405 IDA:UniProtKBFbubble DNA binding
GO:0003690 IDA:UniProtKBFdouble-stranded DNA binding
GO:0004520 IDA:UniProtKBFendodeoxyribonuclease activity
GO:0004519 TAS:ReactomeFendonuclease activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0042803 IPI:UniProtKBFprotein homodimerization activity
GO:0047485 IPI:UniProtKBFprotein N-terminus binding
GO:0003697 IDA:UniProtKBFsingle-stranded DNA binding
GO:0000737 IDA:GOCPDNA catabolic process, endonucleolytic
GO:0006281 TAS:ReactomePDNA repair
GO:0043066 IMP:UniProtKBPnegative regulation of apoptotic process
GO:0006289 TAS:ReactomePnucleotide-excision repair
GO:0000718 TAS:ReactomePnucleotide-excision repair, DNA damage removal
GO:0006295 IDA:UniProtKBPnucleotide-excision repair, DNA incision, 3'-to lesion
GO:0009411 IDA:UniProtKBPresponse to UV
GO:0010225 IMP:UniProtKBPresponse to UV-C
GO:0006283 IMP:UniProtKBPtranscription-coupled nucleotide-excision repair
GO:0009650 IGI:MGIPUV protection
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_216DNA Repair
REACT_311Dual incision reaction in GG-NER
REACT_2222Dual incision reaction in TC-NER
REACT_257Formation of incision complex in GG-NER
REACT_1941Formation of transcription-coupled NER (TC-NER) repair complex
REACT_2253Global Genomic NER (GG-NER)
REACT_1826Nucleotide Excision Repair
REACT_1628Transcription-coupled NER (TC-NER)
SMP Pathway Links
SMP IDDescription
SMP00478Nucleotide Excision Repair
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