MGP Database

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MGP001013

Ontology/Pathway Information

Entrez Gene ID2159
Gene Namecoagulation factor X
Gene Symbol F10
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005788 TAS:ReactomeCendoplasmic reticulum lumen
GO:0005576 NAS:UniProtKBCextracellular region
GO:0005796 TAS:ReactomeCGolgi lumen
GO:0031233 IC:BHF-UCLCintrinsic component of external side of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0005509 IEA:InterProFcalcium ion binding
GO:0005543 IDA:BHF-UCLFphospholipid binding
GO:0004252 IDA:BHF-UCLFserine-type endopeptidase activity
GO:0007596 IC:BHF-UCLPblood coagulation
GO:0007598 TAS:ReactomePblood coagulation, extrinsic pathway
GO:0007597 TAS:ReactomePblood coagulation, intrinsic pathway
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0017187 TAS:ReactomePpeptidyl-glutamic acid carboxylation
GO:0030335 TAS:BHF-UCLPpositive regulation of cell migration
GO:0051897 IDA:BHF-UCLPpositive regulation of protein kinase B signaling
GO:0043687 TAS:ReactomePpost-translational protein modification
GO:0006508 TAS:ReactomePproteolysis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1439Common Pathway
REACT_1573Extrinsic Pathway
REACT_2051Formation of Fibrin Clot (Clotting Cascade)
REACT_1069Gamma carboxylation, hypusine formation and arylsulfatase activation
REACT_1050Gamma-carboxylation of protein precursors
REACT_1132Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
REACT_604Hemostasis
REACT_326Intrinsic Pathway
REACT_17015Metabolism of proteins
REACT_22161Post-translational protein modification
REACT_733Removal of aminoterminal propeptides from gamma-carboxylated proteins
REACT_1906Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
SMP Pathway Links
SMP IDDescription
SMP00269Acenocoumarol Action Pathway
SMP00280Alteplase Action Pathway
SMP00286Aminocaproic Acid Action Pathway
SMP00281Anistreplase Action Pathway
SMP00288Aprotinin Action Pathway
SMP00275Ardeparin Action Pathway
SMP00276Argatroban Action Pathway
SMP00277Bivalirudin Action Pathway
SMP00586Coagulation
SMP00656Dicoumarol Action Pathway
SMP00270Dicumarol Action Pathway
SMP00272Enoxaparin Action Pathway
SMP00273Fondaparinux Action Pathway
SMP00274Heparin Action Pathway
SMP00278Lepirudin Action Pathway
SMP00655Phenindione Action Pathway
SMP00271Phenprocoumon Action Pathway
SMP00285Reteplase Action Pathway
SMP00282Streptokinase Action Pathway
SMP00283Tenecteplase Action Pathway
SMP00287Tranexamic Acid Action Pathway
SMP00284Urokinase Action Pathway
SMP00268Warfarin Action Pathway
SMP00279Ximelagatran Action Pathway
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