MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP001015

Ontology/Pathway Information

Entrez Gene ID2161
Gene Namecoagulation factor XII (Hageman factor)
Gene Symbol F12
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005886 TAS:ReactomeCplasma membrane
GO:0051787 IC:BHF-UCLFmisfolded protein binding
GO:0070009 IEA:EnsemblFserine-type aminopeptidase activity
GO:0004252 IDA:BHF-UCLFserine-type endopeptidase activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0007597 IC:BHF-UCLPblood coagulation, intrinsic pathway
GO:0002542 IDA:BHF-UCLPFactor XII activation
GO:0042730 IEA:UniProtKB-KWPfibrinolysis
GO:0045087 TAS:BHF-UCLPinnate immune response
GO:0002353 IDA:BHF-UCLPplasma kallikrein-kinin cascade
GO:0030194 IDA:BHF-UCLPpositive regulation of blood coagulation
GO:0051919 IDA:BHF-UCLPpositive regulation of fibrinolysis
GO:0010756 IDA:BHF-UCLPpositive regulation of plasminogen activation
GO:0016540 IDA:BHF-UCLPprotein autoprocessing
GO:0016485 IDA:BHF-UCLPprotein processing
GO:0051788 IDA:BHF-UCLPresponse to misfolded protein
GO:0031638 IDA:BHF-UCLPzymogen activation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_2051Formation of Fibrin Clot (Clotting Cascade)
REACT_604Hemostasis
REACT_326Intrinsic Pathway
SMP Pathway Links
SMP IDDescription
SMP00269Acenocoumarol Action Pathway
SMP00280Alteplase Action Pathway
SMP00286Aminocaproic Acid Action Pathway
SMP00281Anistreplase Action Pathway
SMP00288Aprotinin Action Pathway
SMP00275Ardeparin Action Pathway
SMP00276Argatroban Action Pathway
SMP00277Bivalirudin Action Pathway
SMP00586Coagulation
SMP00656Dicoumarol Action Pathway
SMP00270Dicumarol Action Pathway
SMP00272Enoxaparin Action Pathway
SMP00273Fondaparinux Action Pathway
SMP00274Heparin Action Pathway
SMP00278Lepirudin Action Pathway
SMP00655Phenindione Action Pathway
SMP00271Phenprocoumon Action Pathway
SMP00285Reteplase Action Pathway
SMP00282Streptokinase Action Pathway
SMP00283Tenecteplase Action Pathway
SMP00287Tranexamic Acid Action Pathway
SMP00284Urokinase Action Pathway
SMP00268Warfarin Action Pathway
SMP00279Ximelagatran Action Pathway
  logo