MGP Database

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MGP001020

UniProt Annotations

Entry Information
Gene Namefatty acid binding protein 5 (psoriasis-associated)
Protein EntryFABP5_HUMAN
UniProt IDQ01469
SpeciesHuman
Comments
Comment typeDescription
DomainForms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
FunctionHigh specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.
SimilarityBelongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. {ECO:0000305}.
Subcellular LocationCytoplasm.
Tissue SpecificityKeratinocytes; highly expressed in psoriatic skin.
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