MGP Database

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MGP001041

Ontology/Pathway Information

Entrez Gene ID2203
Gene Namefructose-1,6-bisphosphatase 1
Gene Symbol FBP1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 ISS:UniProtKBCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016208 IDA:UniProtKBFAMP binding
GO:0042132 IDA:UniProtKBFfructose 1,6-bisphosphate 1-phosphatase activity
GO:0042802 IPI:IntActFidentical protein binding
GO:0046872 IMP:UniProtKBFmetal ion binding
GO:0048029 ISS:UniProtKBFmonosaccharide binding
GO:0005975 TAS:ReactomePcarbohydrate metabolic process
GO:0035690 IDA:UniProtKBPcellular response to drug
GO:0071286 IDA:UniProtKBPcellular response to magnesium ion
GO:0016311 IDA:UniProtKBPdephosphorylation
GO:0006002 IDA:UniProtKBPfructose 6-phosphate metabolic process
GO:0006000 TAS:ProtIncPfructose metabolic process
GO:0006094 IMP:UniProtKBPgluconeogenesis
GO:0006006 TAS:ReactomePglucose metabolic process
GO:0030308 IDA:UniProtKBPnegative regulation of cell growth
GO:0045820 IDA:UniProtKBPnegative regulation of glycolytic process
GO:0046580 IDA:UniProtKBPnegative regulation of Ras protein signal transduction
GO:0051289 IDA:UniProtKBPprotein homotetramerization
GO:0006111 IMP:UniProtKBPregulation of gluconeogenesis
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_116125Disease
REACT_1520Gluconeogenesis
REACT_723Glucose metabolism
REACT_264090Glycogen storage diseases
REACT_111217Metabolism
REACT_474Metabolism of carbohydrates
REACT_264430Myoclonic epilepsy of Lafora
SMP Pathway Links
SMP IDDescription
SMP00562Fructose-1,6-diphosphatase deficiency
SMP00064Fructose and Mannose Degradation
SMP00725Fructose intolerance, hereditary
SMP00561Fructosuria
SMP00128Gluconeogenesis
SMP00518Glucose-6-phosphate dehydrogenase deficiency
SMP00581Glycogenosis, Type IA. Von gierke disease
SMP00573Glycogenosis, Type IB
SMP00574Glycogenosis, Type IC
SMP00374Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease
SMP00031Pentose Phosphate Pathway
SMP00560Phosphoenolpyruvate carboxykinase deficiency 1 (PEPCK1)
SMP00519Ribose-5-phosphate isomerase deficiency
SMP00520Transaldolase deficiency
SMP00563Triosephosphate isomerase
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