MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP001076

Ontology/Pathway Information

Entrez Gene ID2263
Gene Namefibroblast growth factor receptor 2
Gene Symbol FGFR2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005938 IDA:UniProtKBCcell cortex
GO:0009986 IDA:UniProtKBCcell surface
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0016023 IEA:UniProtKB-SubCellCcytoplasmic membrane-bounded vesicle
GO:0060076 ISS:UniProtKBCexcitatory synapse
GO:0005576 IEA:UniProtKB-SubCellCextracellular region
GO:0005794 IEA:UniProtKB-SubCellCGolgi apparatus
GO:0016021 NAS:UniProtKBCintegral component of membrane
GO:0005887 IDA:UniProtKBCintegral component of plasma membrane
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0016020 NAS:UniProtKBCmembrane
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 TAS:ReactomeCplasma membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0005007 IDA:UniProtKBFfibroblast growth factor-activated receptor activity
GO:0017134 IDA:UniProtKBFfibroblast growth factor binding
GO:0008201 IEA:UniProtKB-KWFheparin binding
GO:0042803 IPI:UniProtKBFprotein homodimerization activity
GO:0004713 NAS:UniProtKBFprotein tyrosine kinase activity
GO:0001525 ISS:UniProtKBPangiogenesis
GO:0006915 IEA:UniProtKB-KWPapoptotic process
GO:0007409 ISS:UniProtKBPaxonogenesis
GO:0060348 ISS:UniProtKBPbone development
GO:0030282 ISS:UniProtKBPbone mineralization
GO:0060349 ISS:UniProtKBPbone morphogenesis
GO:0060667 ISS:UniProtKBPbranch elongation involved in salivary gland morphogenesis
GO:0060670 ISS:UniProtKBPbranching involved in labyrinthine layer morphogenesis
GO:0060442 ISS:UniProtKBPbranching involved in prostate gland morphogenesis
GO:0060445 ISS:UniProtKBPbranching involved in salivary gland morphogenesis
GO:0048755 ISS:UniProtKBPbranching morphogenesis of a nerve
GO:0060449 ISS:UniProtKBPbud elongation involved in lung branching
GO:0007267 ISS:UniProtKBPcell-cell signaling
GO:0045165 ISS:UniProtKBPcell fate commitment
GO:0060365 IEA:EnsemblPcoronal suture morphogenesis
GO:0048565 ISS:UniProtKBPdigestive tract development
GO:0048701 IMP:BHF-UCLPembryonic cranial skeleton morphogenesis
GO:0048557 ISS:UniProtKBPembryonic digestive tract morphogenesis
GO:0048568 ISS:UniProtKBPembryonic organ development
GO:0048562 ISS:UniProtKBPembryonic organ morphogenesis
GO:0009880 ISS:UniProtKBPembryonic pattern specification
GO:0061031 IEA:EnsemblPendodermal digestive tract morphogenesis
GO:0007173 TAS:ReactomePepidermal growth factor receptor signaling pathway
GO:0048730 ISS:UniProtKBPepidermis morphogenesis
GO:0030855 ISS:UniProtKBPepithelial cell differentiation
GO:0060664 ISS:UniProtKBPepithelial cell proliferation involved in salivary gland morphogenesis
GO:0001837 IEA:EnsemblPepithelial to mesenchymal transition
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0008543 IDA:UniProtKBPfibroblast growth factor receptor signaling pathway
GO:0035603 ISS:UniProtKBPfibroblast growth factor receptor signaling pathway involved in hemopoiesis
GO:0060595 ISS:UniProtKBPfibroblast growth factor receptor signaling pathway involved in mammary gland specification
GO:0035602 ISS:UniProtKBPfibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow
GO:0035607 ISS:UniProtKBPfibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
GO:0035604 ISS:UniProtKBPfibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
GO:0022612 ISS:UniProtKBPgland morphogenesis
GO:0031069 ISS:UniProtKBPhair follicle morphogenesis
GO:0045087 TAS:ReactomePinnate immune response
GO:0042472 ISS:UniProtKBPinner ear morphogenesis
GO:0008286 TAS:ReactomePinsulin receptor signaling pathway
GO:0001701 ISS:UniProtKBPin utero embryonic development
GO:0032808 ISS:UniProtKBPlacrimal gland development
GO:0060601 ISS:UniProtKBPlateral sprouting from an epithelium
GO:0070307 IEA:EnsemblPlens fiber cell development
GO:0060174 ISS:UniProtKBPlimb bud formation
GO:0048286 ISS:UniProtKBPlung alveolus development
GO:0060484 ISS:UniProtKBPlung-associated mesenchyme development
GO:0030324 ISS:UniProtKBPlung development
GO:0060463 ISS:UniProtKBPlung lobe morphogenesis
GO:0060615 ISS:UniProtKBPmammary gland bud formation
GO:0003149 ISS:UniProtKBPmembranous septum morphogenesis
GO:0048762 ISS:UniProtKBPmesenchymal cell differentiation
GO:0060915 ISS:UniProtKBPmesenchymal cell differentiation involved in lung development
GO:0060916 ISS:UniProtKBPmesenchymal cell proliferation involved in lung development
GO:0048333 IEA:EnsemblPmesodermal cell differentiation
GO:0030901 ISS:UniProtKBPmidbrain development
GO:0016331 ISS:UniProtKBPmorphogenesis of embryonic epithelium
GO:0035264 ISS:UniProtKBPmulticellular organism growth
GO:0050680 IEA:EnsemblPnegative regulation of epithelial cell proliferation
GO:0045839 IEA:EnsemblPnegative regulation of mitosis
GO:0000122 ISS:UniProtKBPnegative regulation of transcription from RNA polymerase II promoter
GO:0007528 IEA:EnsemblPneuromuscular junction development
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0042476 ISS:UniProtKBPodontogenesis
GO:0021769 ISS:UniProtKBPorbitofrontal cortex development
GO:0035265 ISS:UniProtKBPorgan growth
GO:0009887 ISS:UniProtKBPorgan morphogenesis
GO:0030916 ISS:UniProtKBPotic vesicle formation
GO:0003148 ISS:UniProtKBPoutflow tract septum morphogenesis
GO:0018108 IDA:UniProtKBPpeptidyl-tyrosine phosphorylation
GO:0048015 TAS:ReactomePphosphatidylinositol-mediated signaling
GO:0090263 ISS:UniProtKBPpositive regulation of canonical Wnt signaling pathway
GO:0060045 ISS:UniProtKBPpositive regulation of cardiac muscle cell proliferation
GO:0045787 ISS:UniProtKBPpositive regulation of cell cycle
GO:0051781 ISS:UniProtKBPpositive regulation of cell division
GO:0008284 IDA:UniProtKBPpositive regulation of cell proliferation
GO:0050679 ISS:UniProtKBPpositive regulation of epithelial cell proliferation
GO:0060501 ISS:UniProtKBPpositive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0070374 ISS:UniProtKBPpositive regulation of ERK1 and ERK2 cascade
GO:0043410 IMP:UniProtKBPpositive regulation of MAPK cascade
GO:0002053 ISS:UniProtKBPpositive regulation of mesenchymal cell proliferation
GO:0010518 IMP:UniProtKBPpositive regulation of phospholipase activity
GO:0048661 IEA:EnsemblPpositive regulation of smooth muscle cell proliferation
GO:0045944 ISS:UniProtKBPpositive regulation of transcription from RNA polymerase II promoter
GO:0030177 ISS:UniProtKBPpositive regulation of Wnt signaling pathway
GO:0009791 ISS:UniProtKBPpost-embryonic development
GO:0060527 ISS:UniProtKBPprostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060523 ISS:UniProtKBPprostate epithelial cord elongation
GO:0060512 ISS:UniProtKBPprostate gland morphogenesis
GO:0046777 IDA:UniProtKBPprotein autophosphorylation
GO:0021860 ISS:UniProtKBPpyramidal neuron development
GO:0060687 ISS:UniProtKBPregulation of branching involved in prostate gland morphogenesis
GO:0010453 ISS:UniProtKBPregulation of cell fate commitment
GO:0070372 ISS:UniProtKBPregulation of ERK1 and ERK2 cascade
GO:0040036 ISS:UniProtKBPregulation of fibroblast growth factor receptor signaling pathway
GO:0060688 ISS:UniProtKBPregulation of morphogenesis of a branching structure
GO:0040014 ISS:UniProtKBPregulation of multicellular organism growth
GO:0045667 TAS:UniProtKBPregulation of osteoblast differentiation
GO:0033688 TAS:UniProtKBPregulation of osteoblast proliferation
GO:0008589 ISS:UniProtKBPregulation of smoothened signaling pathway
GO:0051150 ISS:UniProtKBPregulation of smooth muscle cell differentiation
GO:0048608 ISS:UniProtKBPreproductive structure development
GO:0048705 TAS:UniProtKBPskeletal system morphogenesis
GO:0060529 ISS:UniProtKBPsquamous basal epithelial stem cell differentiation involved in prostate gland acinus development
GO:0048489 IEA:EnsemblPsynaptic vesicle transport
GO:0001657 ISS:UniProtKBPureteric bud development
GO:0055010 ISS:UniProtKBPventricular cardiac muscle tissue morphogenesis
GO:0021847 ISS:UniProtKBPventricular zone neuroblast division
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_120863Activated point mutants of FGFR2
REACT_116125Disease
REACT_121255Signaling by FGFR2 amplification mutants
REACT_121155Signaling by FGFR2 mutants
REACT_120736Signaling by FGFR in disease
REACT_121398Signaling by FGFR mutants
  logo