MGP Database

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MGP001080

Ontology/Pathway Information

Entrez Gene ID2271
Gene Namefumarate hydratase
Gene Symbol FH
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 TAS:ProtIncCcytoplasm
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0045239 IEA:InterProCtricarboxylic acid cycle enzyme complex
GO:0004333 EXP:ReactomeFfumarate hydratase activity
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0006106 TAS:ProtIncPfumarate metabolic process
GO:0048873 IEA:EnsemblPhomeostasis of number of cells within a tissue
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006099 TAS:ReactomePtricarboxylic acid cycle
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1785Citric acid cycle (TCA cycle)
REACT_111217Metabolism
REACT_1046Pyruvate metabolism and Citric Acid (TCA) cycle
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
SMP Pathway Links
SMP IDDescription
SMP005492-ketoglutarate dehydrogenase complex deficiency
SMP00057Citric Acid Cycle
SMP00546Congenital lactic acidosis
SMP00547Fumarase deficiency
SMP00548Mitochondrial complex II deficiency
SMP00551Pyruvate dehydrogenase deficiency (E2)
SMP00550Pyruvate dehydrogenase deficiency (E3)
SMP00654Warburg Effect
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