MGP Database

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MGP001089

Ontology/Pathway Information

Entrez Gene ID2316
Gene Namefilamin A, alpha
Gene Symbol FLNA
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0015629 IC:BHF-UCLCactin cytoskeleton
GO:0005884 IEA:EnsemblCactin filament
GO:0097440 IEA:EnsemblCapical dendrite
GO:0030863 IEA:EnsemblCcortical cytoskeleton
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0043198 IEA:EnsemblCdendritic shaft
GO:0005576 TAS:ReactomeCextracellular region
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0016020 IDA:UniProtKBCmembrane
GO:0031523 IDA:MGICMyb complex
GO:0043025 IEA:EnsemblCneuronal cell body
GO:0005634 IDA:UniProtKBCnucleus
GO:0048471 IEA:EnsemblCperinuclear region of cytoplasm
GO:0005886 IDA:BHF-UCLCplasma membrane
GO:0005802 IEA:EnsemblCtrans-Golgi network
GO:0051015 IDA:BHF-UCLFactin filament binding
GO:0034988 IDA:BHF-UCLFFc-gamma receptor I complex binding
GO:0001948 IDA:BHF-UCLFglycoprotein binding
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0042803 IDA:BHF-UCLFprotein homodimerization activity
GO:0048365 IDA:BHF-UCLFRac GTPase binding
GO:0017160 IDA:BHF-UCLFRal GTPase binding
GO:0017048 IDA:BHF-UCLFRho GTPase binding
GO:0004871 IMP:UniProtKBFsignal transducer activity
GO:0031267 IDA:BHF-UCLFsmall GTPase binding
GO:0008134 IPI:UniProtKBFtranscription factor binding
GO:0051764 IDA:BHF-UCLPactin crosslink formation
GO:0031532 IDA:BHF-UCLPactin cytoskeleton reorganization
GO:0007195 IMP:BHF-UCLPadenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0007596 TAS:ReactomePblood coagulation
GO:0034329 TAS:ReactomePcell junction assembly
GO:0042384 IMP:UniProtKBPcilium assembly
GO:0051220 IMP:BHF-UCLPcytoplasmic sequestering of protein
GO:0045022 IEA:EnsemblPearly endosome to late endosome transport
GO:0001837 IEA:EnsemblPepithelial to mesenchymal transition
GO:0045184 IDA:BHF-UCLPestablishment of protein localization
GO:0042789 IEA:EnsemblPmRNA transcription from RNA polymerase II promoter
GO:0042177 IMP:BHF-UCLPnegative regulation of protein catabolic process
GO:0043433 IDA:UniProtKBPnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0030168 TAS:ReactomePplatelet activation
GO:0070527 IMP:UniProtKBPplatelet aggregation
GO:0002576 TAS:ReactomePplatelet degranulation
GO:0043123 IMP:UniProtKBPpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0042993 IMP:UniProtKBPpositive regulation of transcription factor import into nucleus
GO:0034394 IDA:BHF-UCLPprotein localization to cell surface
GO:0050821 IMP:BHF-UCLPprotein stabilization
GO:0043113 IDA:BHF-UCLPreceptor clustering
GO:0090307 IDA:MGIPspindle assembly involved in mitosis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111155Cell-Cell communication
REACT_20649Cell-extracellular matrix interactions
REACT_20676Cell junction organization
REACT_23847GP1b-IX-V activation signalling
REACT_604Hemostasis
REACT_798Platelet activation, signaling and aggregation
REACT_318Platelet degranulation
REACT_1280Response to elevated platelet cytosolic Ca2+
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