MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP001097

Ontology/Pathway Information

Entrez Gene ID2335
Gene Namefibronectin 1
Gene Symbol FN1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016324 IEA:EnsemblCapical plasma membrane
GO:0005605 IEA:EnsemblCbasal lamina
GO:0072562 IDA:UniProtKBCblood microparticle
GO:0005793 IDA:UniProtKBCendoplasmic reticulum-Golgi intermediate compartment
GO:0031012 IDA:UniProtKBCextracellular matrix
GO:0005576 NAS:UniProtKBCextracellular region
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005577 IDA:BHF-UCLCfibrinogen complex
GO:0031093 TAS:ReactomeCplatelet alpha granule lumen
GO:0005518 NAS:UniProtKBFcollagen binding
GO:0008201 NAS:UniProtKBFheparin binding
GO:0005178 IDA:UniProtKBFintegrin binding
GO:0016504 IEA:EnsemblFpeptidase activator activity
GO:0002020 IPI:BHF-UCLFprotease binding
GO:0006953 IEA:UniProtKB-KWPacute-phase response
GO:0001525 IEA:UniProtKB-KWPangiogenesis
GO:0007596 TAS:ReactomePblood coagulation
GO:0007161 IEA:EnsemblPcalcium-independent cell-matrix adhesion
GO:0007155 NAS:UniProtKBPcell adhesion
GO:0007044 IEA:EnsemblPcell-substrate junction assembly
GO:0035987 IDA:UniProtKBPendodermal cell differentiation
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0033622 IMP:UniProtKBPintegrin activation
GO:0050900 TAS:ReactomePleukocyte migration
GO:0018149 IDA:BHF-UCLPpeptide cross-linking
GO:0030168 TAS:ReactomePplatelet activation
GO:0002576 TAS:ReactomePplatelet degranulation
GO:0045773 IEA:EnsemblPpositive regulation of axon extension
GO:0008360 IEA:UniProtKB-KWPregulation of cell shape
GO:0009611 NAS:UniProtKBPresponse to wounding
GO:0034446 IMP:UniProtKBPsubstrate adhesion-dependent cell spreading
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_12051Cell surface interactions at the vascular wall
REACT_118572Degradation of the extracellular matrix
REACT_163906ECM proteoglycans
REACT_150366Elastic fibre formation
REACT_118779Extracellular matrix organization
REACT_160131Fibronectin matrix formation
REACT_15443GRB2:SOS provides linkage to MAPK signaling for Integrins
REACT_604Hemostasis
REACT_15523Integrin alphaIIb beta3 signaling
REACT_13552Integrin cell surface interactions
REACT_150331Molecules associated with elastic fibres
REACT_163874Non-integrin membrane-ECM interactions
REACT_15381p130Cas linkage to MAPK signaling for integrins
REACT_798Platelet activation, signaling and aggregation
REACT_278Platelet Aggregation (Plug Formation)
REACT_318Platelet degranulation
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_111102Signal Transduction
REACT_163942Syndecan interactions
  logo