MGP Database

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MGP001100

Ontology/Pathway Information

Entrez Gene ID2353
Gene NameFBJ murine osteosarcoma viral oncogene homolog
Gene Symbol FOS
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 IEA:UniProtKB-SubCellCcytosol
GO:0005783 IEA:UniProtKB-SubCellCendoplasmic reticulum
GO:0016020 IEA:EnsemblCmembrane
GO:0043005 IEA:EnsemblCneuron projection
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 TAS:ProtIncCnucleus
GO:0005667 IEA:EnsemblCtranscription factor complex
GO:0003690 IEA:EnsemblFdouble-stranded DNA binding
GO:0000979 IEA:EnsemblFRNA polymerase II core promoter sequence-specific DNA binding
GO:0070412 IPI:BHF-UCLFR-SMAD binding
GO:0003700 IDA:BHF-UCLFsequence-specific DNA binding transcription factor activity
GO:0044212 IDA:BHF-UCLFtranscription regulatory region DNA binding
GO:0007568 IEA:EnsemblPaging
GO:0071277 IEA:EnsemblPcellular response to calcium ion
GO:0031668 IEA:EnsemblPcellular response to extracellular stimulus
GO:0032870 IEA:EnsemblPcellular response to hormone stimulus
GO:0034614 IDA:BHF-UCLPcellular response to reactive oxygen species
GO:0001661 IEA:EnsemblPconditioned taste aversion
GO:0006306 TAS:ProtIncPDNA methylation
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0007565 IEA:EnsemblPfemale pregnancy
GO:0006954 TAS:ProtIncPinflammatory response
GO:0045087 TAS:ReactomePinnate immune response
GO:0002755 TAS:ReactomePMyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS:ReactomePMyD88-independent toll-like receptor signaling pathway
GO:0007399 IEA:EnsemblPnervous system development
GO:0045672 IEA:EnsemblPpositive regulation of osteoclast differentiation
GO:0045893 IDA:BHF-UCLPpositive regulation of transcription, DNA-templated
GO:0045944 IEA:EnsemblPpositive regulation of transcription from RNA polymerase II promoter
GO:0051090 TAS:ReactomePregulation of sequence-specific DNA binding transcription factor activity
GO:0006357 TAS:ProtIncPregulation of transcription from RNA polymerase II promoter
GO:0051591 IEA:EnsemblPresponse to cAMP
GO:0009409 IEA:EnsemblPresponse to cold
GO:0051412 IEA:EnsemblPresponse to corticosterone
GO:0034097 IEA:EnsemblPresponse to cytokine
GO:0042493 IEA:EnsemblPresponse to drug
GO:0009629 IEA:EnsemblPresponse to gravity
GO:0035902 IEA:EnsemblPresponse to immobilization stress
GO:0009416 IEA:EnsemblPresponse to light stimulus
GO:0032496 IEA:EnsemblPresponse to lipopolysaccharide
GO:0009612 IEA:EnsemblPresponse to mechanical stimulus
GO:0032570 IEA:EnsemblPresponse to progesterone
GO:0009636 IEA:EnsemblPresponse to toxic substance
GO:0035914 IEA:EnsemblPskeletal muscle cell differentiation
GO:0030431 IEA:EnsemblPsleep
GO:0060395 IDA:BHF-UCLPSMAD protein signal transduction
GO:0051403 TAS:ReactomePstress-activated MAPK cascade
GO:0034166 TAS:ReactomePtoll-like receptor 10 signaling pathway
GO:0034134 TAS:ReactomePtoll-like receptor 2 signaling pathway
GO:0034138 TAS:ReactomePtoll-like receptor 3 signaling pathway
GO:0034142 TAS:ReactomePtoll-like receptor 4 signaling pathway
GO:0034146 TAS:ReactomePtoll-like receptor 5 signaling pathway
GO:0034162 TAS:ReactomePtoll-like receptor 9 signaling pathway
GO:0002224 TAS:ReactomePtoll-like receptor signaling pathway
GO:0038123 TAS:ReactomePtoll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS:ReactomePtoll-like receptor TLR6:TLR2 signaling pathway
GO:0006366 TAS:ProtIncPtranscription from RNA polymerase II promoter
GO:0007179 IDA:BHF-UCLPtransforming growth factor beta receptor signaling pathway
GO:0035666 TAS:ReactomePTRIF-dependent toll-like receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6890Activated TLR4 signalling
REACT_21326Activation of the AP-1 family of transcription factors
REACT_120956Cellular responses to stress
REACT_169274Cellular Senescence
REACT_163936Fc epsilon receptor (FCERI) signaling
REACT_163701FCERI mediated MAPK activation
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_21308MAP kinase activation in TLR cascade
REACT_21328MAPK targets/ Nuclear events mediated by MAP kinases
REACT_27215MyD88 cascade initiated on plasma membrane
REACT_25222MyD88 dependent cascade initiated on endosome
REACT_6809MyD88-independent cascade
REACT_6788MyD88:Mal cascade initiated on plasma membrane
REACT_169436Oxidative Stress Induced Senescence
REACT_169168Senescence-Associated Secretory Phenotype (SASP)
REACT_9027Toll Like Receptor 10 (TLR10) Cascade
REACT_7980Toll Like Receptor 2 (TLR2) Cascade
REACT_6783Toll Like Receptor 3 (TLR3) Cascade
REACT_6894Toll Like Receptor 4 (TLR4) Cascade
REACT_9061Toll Like Receptor 5 (TLR5) Cascade
REACT_9020Toll Like Receptor 7/8 (TLR7/8) Cascade
REACT_9047Toll Like Receptor 9 (TLR9) Cascade
REACT_6966Toll-Like Receptors Cascades
REACT_8005Toll Like Receptor TLR1:TLR2 Cascade
REACT_8006Toll Like Receptor TLR6:TLR2 Cascade
REACT_25024TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
REACT_25281TRIF-mediated TLR3/TLR4 signaling
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