MGP Database

MGP001107

Record overview

MGPD ID	MGP001107
Gene ID	2488
Species	Homo sapiens (Human)
Gene Name	follicle stimulating hormone, beta polypeptide
Gene Symbol	FSHB
Alternate names	follitropin subunit beta; FSH-B; FSH-beta; follicle-stimulating hormone beta subunit; follitropin beta chain; follitropin, beta chain;
Chromosome	11
Map Location	11p13
Summary	The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Orthologs	View orthologs and multiple alignments for FSHB

Proteins

follitropin subunit beta precursor

Refseq ID:	NP_000501
Protein GI:	4503791
UniProt ID:	P01225
mRNA ID:	NM_000510
Length:	129
RefSeq Status:

`MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKDPARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQC HCGKCDSDSTDCTVRGLGPSYCSFGEMKE`

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2233
peptide sequence: 
MKTLQFFFLFCCWKAICC

mat_peptide: 19..129
product: follitropin subunit beta
calculated_mol_wt: 12485
peptide sequence: 
NSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKDPARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLG
PSYCSFGEMKE

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2233
peptide sequence: 
MKTLQFFFLFCCWKAICC

mat_peptide: 19..129
product: follitropin subunit beta
calculated_mol_wt: 12485
peptide sequence: 
NSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKDPARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLG
PSYCSFGEMKE

follitropin subunit beta precursor

Refseq ID:	NP_001018090
Protein GI:	66528995
UniProt ID:	P01225
mRNA ID:	NM_001018080
Length:	129
RefSeq Status:

Protein sequence is identical to GI:4503791 (mRNA isoform)

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2233
peptide sequence: 
MKTLQFFFLFCCWKAICC

mat_peptide: 19..129
product: follitropin subunit beta
calculated_mol_wt: 12485
peptide sequence: 
NSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKDPARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLG
PSYCSFGEMKE