MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP001111

Record overview

MGPD IDMGP001111
Gene ID2512
SpeciesHomo sapiens (Human)
Gene Nameferritin, light polypeptide
Gene Symbol FTL
SynonymsLFTD; NBIA3;
Alternate namesferritin light chain; ferritin L subunit; ferritin L-chain; ferritin light polypeptide-like 3;
Chromosome19
Map Location19q13.33
SummaryThis gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for FTL

Proteins

ferritin light chain
Refseq ID:NP_000137
Protein GI:20149498
UniProt ID:P02792
mRNA ID:NM_000146
Length:175
RefSeq Status:
MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAA
MALEKKLNQALLDLHALGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFERLTLKHD
 
  logo