MGP Database

MGP001114

Record overview

MGPD ID	MGP001114
Gene ID	2520
Species	Homo sapiens (Human)
Gene Name	gastrin
Gene Symbol	GAST
Synonyms	GAS;
Alternate names	gastrin; preprogastrin;
Chromosome	17
Map Location	17q21
Summary	Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq, Jul 2008]
Orthologs	View orthologs and multiple alignments for GAST

Proteins

gastrin preproprotein

Refseq ID:	NP_000796
Protein GI:	4503923
UniProt ID:	P01350
mRNA ID:	NM_000805
Length:	101
RefSeq Status:

`MQRLCVYVLIFALALAAFSEASWKPRSQQPDAPLGTGANRDLELPWLEQQGPASHHRRQLGPQGPPHLVADPSKKQGPWLEEEEEAYGWMDFGRRSAEDE N`

sig_peptide: 1..21
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2330
peptide sequence: 
MQRLCVYVLIFALALAAFSEA

mat_peptide: 22..92
product: Gastrin-71
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P01350.1)
calculated_mol_wt: 8067
peptide sequence: 
SWKPRSQQPDAPLGTGANRDLELPWLEQQGPASHHRRQLGPQGPPHLVADPSKKQGPWLEEEEEAYGWMDF

mat_peptide: 41..92
product: Gastrin-52
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P01350.1)
calculated_mol_wt: 6019
peptide sequence: 
DLELPWLEQQGPASHHRRQLGPQGPPHLVADPSKKQGPWLEEEEEAYGWMDF

mat_peptide: 59..92
product: Big gastrin
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P01350.1)
calculated_mol_wt: 3867
peptide sequence: 
QLGPQGPPHLVADPSKKQGPWLEEEEEAYGWMDF

mat_peptide: 76..92
product: Gastrin
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P01350.1)
calculated_mol_wt: 2116
peptide sequence: 
QGPWLEEEEEAYGWMDF

mat_peptide: 79..92
product: Gastrin-14
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P01350.1)
calculated_mol_wt: 1834
peptide sequence: 
WLEEEEEAYGWMDF

mat_peptide: 87..92
product: Gastrin-6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P01350.1)
calculated_mol_wt: 818
peptide sequence: 
YGWMDF