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MGP001117

Record overview

MGPD IDMGP001117
Gene ID2532
SpeciesHomo sapiens (Human)
Gene Nameatypical chemokine receptor 1 (Duffy blood group)
Gene Symbol ACKR1
SynonymsFY; Dfy; GPD; DARC; GpFy; CCBP1; CD234; WBCQ1;
Alternate namesatypical chemokine receptor 1; Duffy blood group antigen; Duffy blood group, atypical chemokine receptor; Duffy blood group, chemokine receptor; Fy glycoprotein; glycoprotein D; plasmodium vivax receptor;
Chromosome1
Map Location1q21-q22
SummaryThe protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ACKR1

Proteins

atypical chemokine receptor 1 isoform a
Refseq ID:NP_001116423
Protein GI:171846251
UniProt ID:Q16570
mRNA ID:NM_001122951
Length:338
RefSeq Status:
MASSGYVLQAELSPSTENSSQLDFEDVWNSSYGVNDSFPDGDYGANLEAAAPCHSCNLLDDSALPFFILTSVLGILASSTVLFMLFRPLFRWQLCPGWPV
LAQLAVGSALFSIVVPVLAPGLGSTRSSALCSLGYCVWYGSAFAQALLLGCHASLGHRLGAGQVPGLTLGLTVGIWGVAALLTLPVTLASGASGGLCTLI
YSTELKALQATHTVACLAIFVLLPLGLFGAKGLKKALGMGPGPWMNILWAWFIFWWPHGVVLGLDFLVRSKLLLLSTCLAQQALDLLLNLAEALAILHCV
ATPLLLALFCHQATRTLLPSLPLPEGWSSHLDTLGSKS
 
atypical chemokine receptor 1 isoform b
Refseq ID:NP_002027
Protein GI:42822887
UniProt ID:Q16570
mRNA ID:NM_002036
Length:336
RefSeq Status:
MGNCLHRAELSPSTENSSQLDFEDVWNSSYGVNDSFPDGDYGANLEAAAPCHSCNLLDDSALPFFILTSVLGILASSTVLFMLFRPLFRWQLCPGWPVLA
QLAVGSALFSIVVPVLAPGLGSTRSSALCSLGYCVWYGSAFAQALLLGCHASLGHRLGAGQVPGLTLGLTVGIWGVAALLTLPVTLASGASGGLCTLIYS
TELKALQATHTVACLAIFVLLPLGLFGAKGLKKALGMGPGPWMNILWAWFIFWWPHGVVLGLDFLVRSKLLLLSTCLAQQALDLLLNLAEALAILHCVAT
PLLLALFCHQATRTLLPSLPLPEGWSSHLDTLGSKS
 
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