MGP Database

MGP001121

Record overview

MGPD ID	MGP001121
Gene ID	2537
Species	Homo sapiens (Human)
Gene Name	interferon, alpha-inducible protein 6
Gene Symbol	IFI6
Synonyms	6-16; G1P3; FAM14C; IFI616; IFI-6-16;
Alternate names	interferon alpha-inducible protein 6; interferon, alpha-inducible protein clone IFI-6-16; interferon-induced protein 6-16;
Chromosome	1
Map Location	1p35
Summary	This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described. [provided by RefSeq, Jul 2008]
Orthologs	View orthologs and multiple alignments for IFI6

Proteins

interferon alpha-inducible protein 6 isoform a precursor

Refseq ID:	NP_002029
Protein GI:	13259552
UniProt ID:	P09912
mRNA ID:	NM_002038
Length:	130
RefSeq Status:

`MRQKAVSLFLCYLLLFTCSGVEAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGLPALGFTGAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLG AGGSSVVIGNIGALMGYATHKYLDSEEDEE`

interferon alpha-inducible protein 6 isoform b precursor
`sig_peptide: 1..23 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2593 peptide sequence: MRQKAVSLFLCYLLLFTCSGVEA`

Refseq ID:	NP_075010
Protein GI:	13259548
UniProt ID:	P09912
mRNA ID:	NM_022872
Length:	134
RefSeq Status:

`MRQKAVSLFLCYLLLFTCSGVEAGENAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGLPALGFTGAGIAANSVAASLMSWSAILNGGGVPAGGLVATL QSLGAGGSSVVIGNIGALMGYATHKYLDSEEDEE`

sig_peptide: 1..23
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2593
peptide sequence: 
MRQKAVSLFLCYLLLFTCSGVEA

sig_peptide: 1..23
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2593
peptide sequence: 
MRQKAVSLFLCYLLLFTCSGVEA

sig_peptide: 1..23
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2593
peptide sequence: 
MRQKAVSLFLCYLLLFTCSGVEA

interferon alpha-inducible protein 6 isoform c precursor

Refseq ID:	NP_075011
Protein GI:	13259550
UniProt ID:	P09912
mRNA ID:	NM_022873
Length:	138
RefSeq Status:

`MRQKAVSLFLCYLLLFTCSGVEAGENAGKDAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGLPALGFTGAGIAANSVAASLMSWSAILNGGGVPAGGL VATLQSLGAGGSSVVIGNIGALMGYATHKYLDSEEDEE`

sig_peptide: 1..23
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2593
peptide sequence: 
MRQKAVSLFLCYLLLFTCSGVEA

sig_peptide: 1..23
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2593
peptide sequence: 
MRQKAVSLFLCYLLLFTCSGVEA