MGP Database

MGP001122

Ontology/Pathway Information

Entrez Gene ID	2538
Gene Name	glucose-6-phosphatase, catalytic subunit
Gene Symbol	G6PC
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005789	TAS:Reactome	C	endoplasmic reticulum membrane
GO:0030176	TAS:UniProtKB	C	integral component of endoplasmic reticulum membrane
GO:0016021	IDA:UniProtKB	C	integral component of membrane
GO:0004346	IDA:UniProtKB	F	glucose-6-phosphatase activity
GO:0042301	IMP:UniProtKB	F	phosphate ion binding
GO:0016773	IEA:Ensembl	F	phosphotransferase activity, alcohol group as acceptor
GO:0005975	TAS:Reactome	P	carbohydrate metabolic process
GO:0042632	IEA:Ensembl	P	cholesterol homeostasis
GO:0006094	IMP:UniProtKB	P	gluconeogenesis
GO:0051156	IEA:Ensembl	P	glucose 6-phosphate metabolic process
GO:0015760	IEA:Ensembl	P	glucose-6-phosphate transport
GO:0042593	IMP:UniProtKB	P	glucose homeostasis
GO:0015758	TAS:Reactome	P	glucose transport
GO:0005980	IEA:Ensembl	P	glycogen catabolic process
GO:0005977	TAS:ProtInc	P	glycogen metabolic process
GO:0008645	TAS:Reactome	P	hexose transport
GO:0035264	IEA:Ensembl	P	multicellular organism growth
GO:0046838	IEA:Ensembl	P	phosphorylated carbohydrate dephosphorylation
GO:0010468	IEA:Ensembl	P	regulation of gene expression
GO:0032094	IEA:Ensembl	P	response to food
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0008202	IEA:Ensembl	P	steroid metabolic process
GO:0055085	TAS:Reactome	P	transmembrane transport
GO:0006641	IEA:Ensembl	P	triglyceride metabolic process
GO:0046415	IEA:Ensembl	P	urate metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_116125	Disease
REACT_212	Glucose transport
REACT_264090	Glycogen storage diseases
REACT_9441	Hexose transport
REACT_111217	Metabolism
REACT_474	Metabolism of carbohydrates
REACT_264430	Myoclonic epilepsy of Lafora
REACT_19118	SLC-mediated transmembrane transport
REACT_15518	Transmembrane transport of small molecules

SMP Pathway Links

SMP ID	Description
SMP00579	Congenital disorder of glycosylation CDG-IId
SMP00572	Fanconi-bickel syndrome
SMP00562	Fructose-1,6-diphosphatase deficiency
SMP00043	Galactose Metabolism
SMP00182	Galactosemia
SMP00128	Gluconeogenesis
SMP00580	GLUT-1 deficiency syndrome
SMP00581	Glycogenosis, Type IA. Von gierke disease
SMP00573	Glycogenosis, Type IB
SMP00574	Glycogenosis, Type IC
SMP00531	Glycogenosis, Type VII. Tarui disease
SMP00374	Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease
SMP00040	Glycolysis
SMP00444	Lactose Synthesis
SMP00560	Phosphoenolpyruvate carboxykinase deficiency 1 (PEPCK1)
SMP00563	Triosephosphate isomerase