MGP Database

MGP001123

Ontology/Pathway Information

Entrez Gene ID2539
Gene Nameglucose-6-phosphate dehydrogenase
Gene Symbol G6PD
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005813 IDA:HPACcentrosome
GO:0005737 IDA:LIFEdbCcytoplasm
GO:0009898 IDA:BHF-UCLCcytoplasmic side of plasma membrane
GO:0005829 IDA:BHF-UCLCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0016020 IDA:UniProtKBCmembrane
GO:0005815 IDA:HPACmicrotubule organizing center
GO:0005634 IEA:EnsemblCnucleus
GO:0004345 IDA:UniProtKBFglucose-6-phosphate dehydrogenase activity
GO:0005536 IDA:BHF-UCLFglucose binding
GO:0050661 IDA:BHF-UCLFNADP binding
GO:0042803 IPI:BHF-UCLFprotein homodimerization activity
GO:0005975 TAS:ReactomePcarbohydrate metabolic process
GO:0034599 IMP:BHF-UCLPcellular response to oxidative stress
GO:0006695 IMP:BHF-UCLPcholesterol biosynthetic process
GO:0001816 IMP:BHF-UCLPcytokine production
GO:0043249 IMP:BHF-UCLPerythrocyte maturation
GO:0051156 IDA:UniProtKBPglucose 6-phosphate metabolic process
GO:0006749 IMP:BHF-UCLPglutathione metabolic process
GO:0006629 TAS:BHF-UCLPlipid metabolic process
GO:0006740 IMP:BHF-UCLPNADPH regeneration
GO:0006739 IDA:UniProtKBPNADP metabolic process
GO:0010734 IMP:BHF-UCLPnegative regulation of protein glutathionylation
GO:0055114 IMP:BHF-UCLPoxidation-reduction process
GO:0019322 IDA:BHF-UCLPpentose biosynthetic process
GO:0006098 IDA:BHF-UCLPpentose-phosphate shunt
GO:0009051 IMP:BHF-UCLPpentose-phosphate shunt, oxidative branch
GO:0043523 IEA:EnsemblPregulation of neuron apoptotic process
GO:0045471 IEA:EnsemblPresponse to ethanol
GO:0032094 IEA:EnsemblPresponse to food
GO:0014070 IEA:EnsemblPresponse to organic cyclic compound
GO:0046390 IMP:BHF-UCLPribose phosphate biosynthetic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0021762 IEP:UniProtKBPsubstantia nigra development
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_116125Disease
REACT_264090Glycogen storage diseases
REACT_111217Metabolism
REACT_474Metabolism of carbohydrates
REACT_264430Myoclonic epilepsy of Lafora
REACT_1859Pentose phosphate pathway (hexose monophosphate shunt)
SMP Pathway Links
SMP IDDescription
SMP00518Glucose-6-phosphate dehydrogenase deficiency
SMP00031Pentose Phosphate Pathway
SMP00519Ribose-5-phosphate isomerase deficiency
SMP00520Transaldolase deficiency
SMP00654Warburg Effect
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