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MGP001124

Record overview

MGPD IDMGP001124
Gene ID2542
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 37 (glucose-6-phosphate transporter), member 4
Gene Symbol SLC37A4
SynonymsG6PT1; G6PT2; G6PT3; GSD1b; GSD1c; GSD1d; TRG19; TRG-19; PRO0685;
Alternate namesglucose-6-phosphate translocase; glucose-5-phosphate transporter; glucose-6-phosphatase, transport (glucose) protein 3; glucose-6-phosphatase, transport (glucose-6-phosphate) protein 1; glucose-6-phosphatase, transport (phosphate/pyrophosphate) protein 2; microsomal glucose-6-phosphate transporter; transformation-related gene 19 protein;
Chromosome11
Map Location11q23.3
SummaryThis gene regulates glucose-6-phosphate transport from the cytoplasm to the lumen of the endoplasmic reticulum, in order to maintain glucose homeostasis. It also plays a role in ATP-mediated calcium sequestration in the lumen of the endoplasmic reticulum. Mutations in this gene have been associated with various forms of glycogen storage disease. Alternative splicing in this gene results in multiple transcript variants.[provided by RefSeq, Aug 2009]
OrthologsView orthologs and multiple alignments for SLC37A4

Proteins

glucose-6-phosphate translocase isoform 1
Refseq ID:NP_001157749
Protein GI:256219483
UniProt ID:O43826
mRNA ID:NM_001164277
Length:429
RefSeq Status:
MAAQGYGYYRTVIFSAMFGGYSLYYFNRKTFSFVMPSLVEEIPLDKDDLGFITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNIFFAWSSTV
PVFAALWFLNGLAQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNLAGGLGPILATILAQSYSWRSTLALSGALCVVVSFLCLLLIHNEPADVGLRNLD
PMPSEGKKGSLKEESTLQELLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQEKGQSALVGSSYMSALEVGGLVGSIAAGYLSDRAMAKAGLSNYGNPR
HGLLLFMMAGMTVSMYLFRVTVTSDSPKLWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVA
EVICAASTAAFFLLRNIRTKMGRVSKKAE
 
glucose-6-phosphate translocase isoform 1
Refseq ID:NP_001157752
Protein GI:256219598
UniProt ID:O43826
mRNA ID:NM_001164280
Length:429
RefSeq Status:
Protein sequence is identical to GI:256219483 (mRNA isoform)
 
glucose-6-phosphate translocase isoform 1
Refseq ID:NP_001458
Protein GI:4503847
UniProt ID:O43826
mRNA ID:NM_001467
Length:429
RefSeq Status:
Protein sequence is identical to GI:256219483 (mRNA isoform)
 
glucose-6-phosphate translocase isoform 2
Refseq ID:NP_001157750
Protein GI:256219543
UniProt ID:O43826
mRNA ID:NM_001164278
Length:451
RefSeq Status:
MAAQGYGYYRTVIFSAMFGGYSLYYFNRKTFSFVMPSLVEEIPLDKDDLGFITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNIFFAWSSTV
PVFAALWFLNGLAQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNLAGGLGPILATILAQSYSWRSTLALSGALCVVVSFLCLLLIHNEPADVGLRNLD
PMPSEGKKGSLKEESTLQELLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQEKGQSALVGSSYMSALEVGGLVGSIAAGYLSDRAMAKAGLSNYGNPR
HGLLLFMMAGMTVSMYLFRVTVTSDSPKDVAFWTLALHPLAELTGFTEHELWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGF
LAGLPFSTIAKHYSWSTAFWVAEVICAASTAAFFLLRNIRTKMGRVSKKAE
 
glucose-6-phosphate translocase isoform 3
Refseq ID:NP_001157751
Protein GI:256219564
UniProt ID:O43826
mRNA ID:NM_001164279
Length:356
RefSeq Status:
MSARWLFSSGLLLVGLVNIFFAWSSTVPVFAALWFLNGLAQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNLAGGLGPILATILAQSYSWRSTLALSG
ALCVVVSFLCLLLIHNEPADVGLRNLDPMPSEGKKGSLKEESTLQELLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQEKGQSALVGSSYMSALEVGG
LVGSIAAGYLSDRAMAKAGLSNYGNPRHGLLLFMMAGMTVSMYLFRVTVTSDSPKLWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMA
NVGGFLAGLPFSTIAKHYSWSTAFWVAEVICAASTAAFFLLRNIRTKMGRVSKKAE
 
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