MGP Database

MGP001154

Ontology/Pathway Information

Entrez Gene ID	2593
Gene Name	guanidinoacetate N-methyltransferase
Gene Symbol	GAMT
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005829	TAS:Reactome	C	cytosol
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0030731	IMP:UniProtKB	F	guanidinoacetate N-methyltransferase activity
GO:0008168	TAS:ProtInc	F	methyltransferase activity
GO:0034641	TAS:Reactome	P	cellular nitrogen compound metabolic process
GO:0006601	IDA:UniProtKB	P	creatine biosynthetic process
GO:0006600	TAS:Reactome	P	creatine metabolic process
GO:0006936	TAS:ProtInc	P	muscle contraction
GO:0009887	IEA:Ensembl	P	organ morphogenesis
GO:0040014	IEA:Ensembl	P	regulation of multicellular organism growth
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0007283	IEA:Ensembl	P	spermatogenesis

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_813	Creatine metabolism
REACT_111217	Metabolism
REACT_13	Metabolism of amino acids and derivatives

SMP Pathway Links

SMP ID	Description
SMP00721	3-Phosphoglycerate dehydrogenase deficiency
SMP00020	Arginine and Proline Metabolism
SMP00362	Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)
SMP00504	Creatine deficiency, guanidinoacetate methyltransferase deficiency
SMP00179	Dihydropyrimidine Dehydrogenase Deficiency (DHPD)
SMP00242	Dimethylglycine Dehydrogenase Deficiency
SMP00484	Dimethylglycinuria
SMP00004	Glycine and Serine Metabolism
SMP00188	Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency)
SMP00485	Hyperglycinemia, non-ketotic
SMP00506	Hyperornithinemia-hyperammonemia-homocitrullinuria [HHH-syndrome]
SMP00505	Hyperornithinemia with gyrate atrophy (HOGA)
SMP00361	Hyperprolinemia Type I
SMP00360	Hyperprolinemia Type II
SMP00507	L-arginine:glycine amidinotransferase deficiency
SMP00223	Non Ketotic Hyperglycinemia
SMP00363	Ornithine Aminotransferase Deficiency (OAT Deficiency)
SMP00207	Prolidase Deficiency (PD)
SMP00208	Prolinemia Type II
SMP00244	Sarcosinemia