MGP Database

MGP001158

Ontology/Pathway Information

Entrez Gene ID	2619
Gene Name	growth arrest-specific 1
Gene Symbol	GAS1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0046658	ISS:UniProtKB	C	anchored component of plasma membrane
GO:0016021	NAS:UniProtKB	C	integral component of membrane
GO:0005886	IDA:UniProtKB	C	plasma membrane
GO:0007411	IEA:Ensembl	P	axon guidance
GO:0043010	IEA:Ensembl	P	camera-type eye development
GO:0007050	IEA:UniProtKB-KW	P	cell cycle arrest
GO:0045165	ISS:UniProtKB	P	cell fate commitment
GO:0035924	IEP:UniProtKB	P	cellular response to vascular endothelial growth factor stimulus
GO:0021587	IEA:Ensembl	P	cerebellum morphogenesis
GO:0048589	ISS:UniProtKB	P	developmental growth
GO:0021904	IEA:Ensembl	P	dorsal/ventral neural tube patterning
GO:0048701	IEA:Ensembl	P	embryonic cranial skeleton morphogenesis
GO:0042733	IEA:Ensembl	P	embryonic digit morphogenesis
GO:0048592	IEA:Ensembl	P	eye morphogenesis
GO:0042474	IEA:Ensembl	P	middle ear morphogenesis
GO:0030308	IEA:Ensembl	P	negative regulation of cell growth
GO:0050680	IEA:Ensembl	P	negative regulation of epithelial cell proliferation
GO:2001240	IEA:Ensembl	P	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:0045930	IDA:UniProtKB	P	negative regulation of mitotic cell cycle
GO:0010955	IMP:UniProtKB	P	negative regulation of protein processing
GO:0045879	IEA:Ensembl	P	negative regulation of smoothened signaling pathway
GO:0042476	IEA:Ensembl	P	odontogenesis
GO:0042473	IEA:Ensembl	P	outer ear morphogenesis
GO:0060021	IEA:Ensembl	P	palate development
GO:0050679	IEA:Ensembl	P	positive regulation of epithelial cell proliferation
GO:0002053	IEA:Ensembl	P	positive regulation of mesenchymal cell proliferation
GO:0045880	IEA:Ensembl	P	positive regulation of smoothened signaling pathway
GO:0012501	IEA:Ensembl	P	programmed cell death
GO:0042981	ISS:UniProtKB	P	regulation of apoptotic process
GO:0060628	IMP:UniProtKB	P	regulation of ER to Golgi vesicle-mediated transport
GO:0008589	ISS:UniProtKB	P	regulation of smoothened signaling pathway

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_268718	Hedgehog 'on' state
REACT_268573	Ligand-receptor interactions
REACT_264508	Signaling by Hedgehog
REACT_111102	Signal Transduction