MGP Database

MGP001163

Ontology/Pathway Information

Entrez Gene ID	2625
Gene Name	GATA binding protein 3
Gene Symbol	GATA3
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0000790	IDA:BHF-UCL	C	nuclear chromatin
GO:0005730	IDA:HPA	C	nucleolus
GO:0005654	IDA:HPA	C	nucleoplasm
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0000987	IDA:UniProtKB	F	core promoter proximal region sequence-specific DNA binding
GO:0001046	IDA:UniProtKB	F	core promoter sequence-specific DNA binding
GO:0003677	TAS:ProtInc	F	DNA binding
GO:0070888	IDA:BHF-UCL	F	E-box binding
GO:0001158	IEA:Ensembl	F	enhancer sequence-specific DNA binding
GO:0071837	IPI:UniProtKB	F	HMG box domain binding
GO:0001071	IDA:UniProtKB	F	nucleic acid binding transcription factor activity
GO:0001078	IMP:UniProtKB	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001077	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0000979	IEA:Ensembl	F	RNA polymerase II core promoter sequence-specific DNA binding
GO:0003700	TAS:ProtInc	F	sequence-specific DNA binding transcription factor activity
GO:0003713	IDA:UniProtKB	F	transcription coactivator activity
GO:0008134	IPI:BHF-UCL	F	transcription factor binding
GO:0044212	IDA:UniProtKB	F	transcription regulatory region DNA binding
GO:0000976	IDA:UniProtKB	F	transcription regulatory region sequence-specific DNA binding
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0048646	ISS:UniProtKB	P	anatomical structure formation involved in morphogenesis
GO:0009653	TAS:ProtInc	P	anatomical structure morphogenesis
GO:0003180	ISS:UniProtKB	P	aortic valve morphogenesis
GO:0007411	IEA:Ensembl	P	axon guidance
GO:0007596	TAS:Reactome	P	blood coagulation
GO:0061290	ISS:UniProtKB	P	canonical Wnt signaling pathway involved in metanephric kidney development
GO:0003215	ISS:UniProtKB	P	cardiac right ventricle morphogenesis
GO:0001709	ISS:UniProtKB	P	cell fate determination
GO:0048469	IEA:Ensembl	P	cell maturation
GO:0071773	IEA:Ensembl	P	cellular response to BMP stimulus
GO:0035457	IEP:UniProtKB	P	cellular response to interferon-alpha
GO:0071353	IEP:UniProtKB	P	cellular response to interleukin-4
GO:0071356	IEP:UniProtKB	P	cellular response to tumor necrosis factor
GO:0006952	TAS:ProtInc	P	defense response
GO:0048589	IEA:Ensembl	P	developmental growth
GO:0043583	IMP:UniProtKB	P	ear development
GO:0035162	IEA:Ensembl	P	embryonic hemopoiesis
GO:0030218	IEA:Ensembl	P	erythrocyte differentiation
GO:0006959	IEA:Ensembl	P	humoral immune response
GO:0045087	IEA:UniProtKB-KW	P	innate immune response
GO:0042472	IEA:Ensembl	P	inner ear morphogenesis
GO:0072643	IEA:Ensembl	P	interferon-gamma secretion
GO:0072602	IEA:Ensembl	P	interleukin-4 secretion
GO:0001701	IEA:Ensembl	P	in utero embryonic development
GO:0001822	IMP:UniProtKB	P	kidney development
GO:0002088	IEA:Ensembl	P	lens development in camera-type eye
GO:0072676	IDA:UniProtKB	P	lymphocyte migration
GO:0008584	ISS:UniProtKB	P	male gonad development
GO:0060374	IEA:Ensembl	P	mast cell differentiation
GO:0060231	IDA:UniProtKB	P	mesenchymal to epithelial transition
GO:0001823	ISS:UniProtKB	P	mesonephros development
GO:0045786	IMP:UniProtKB	P	negative regulation of cell cycle
GO:2000146	IMP:UniProtKB	P	negative regulation of cell motility
GO:0008285	ISS:UniProtKB	P	negative regulation of cell proliferation
GO:2000607	ISS:UniProtKB	P	negative regulation of cell proliferation involved in mesonephros development
GO:2000352	IMP:UniProtKB	P	negative regulation of endothelial cell apoptotic process
GO:0045599	IMP:UniProtKB	P	negative regulation of fat cell differentiation
GO:2000703	ISS:UniProtKB	P	negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
GO:2000734	ISS:UniProtKB	P	negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
GO:0050728	IMP:UniProtKB	P	negative regulation of inflammatory response
GO:0032689	IEA:Ensembl	P	negative regulation of interferon-gamma production
GO:0032703	IEA:Ensembl	P	negative regulation of interleukin-2 production
GO:0033600	IDA:UniProtKB	P	negative regulation of mammary gland epithelial cell proliferation
GO:0045892	IMP:UniProtKB	P	negative regulation of transcription, DNA-templated
GO:0072179	ISS:UniProtKB	P	nephric duct formation
GO:0072178	ISS:UniProtKB	P	nephric duct morphogenesis
GO:0001764	IEA:Ensembl	P	neuron migration
GO:0042421	ISS:UniProtKB	P	norepinephrine biosynthetic process
GO:0071599	IEA:Ensembl	P	otic vesicle development
GO:0060017	IEA:Ensembl	P	parathyroid gland development
GO:0035898	IEA:Ensembl	P	parathyroid hormone secretion
GO:0060037	ISS:UniProtKB	P	pharyngeal system development
GO:0014065	ISS:UniProtKB	P	phosphatidylinositol 3-kinase signaling
GO:0010595	IMP:UniProtKB	P	positive regulation of endothelial cell migration
GO:2000667	IDA:UniProtKB	P	positive regulation of interleukin-13 secretion
GO:0032753	ISS:UniProtKB	P	positive regulation of interleukin-4 production
GO:2000664	IDA:UniProtKB	P	positive regulation of interleukin-5 secretion
GO:0051897	IMP:UniProtKB	P	positive regulation of protein kinase B signaling
GO:0009967	IMP:UniProtKB	P	positive regulation of signal transduction
GO:0045582	ISS:UniProtKB	P	positive regulation of T cell differentiation
GO:2000611	IMP:UniProtKB	P	positive regulation of thyroid hormone generation
GO:0045893	IDA:UniProtKB	P	positive regulation of transcription, DNA-templated
GO:0045944	IDA:UniProtKB	P	positive regulation of transcription from RNA polymerase II promoter
GO:2000679	IMP:UniProtKB	P	positive regulation of transcription regulatory region DNA binding
GO:0072107	ISS:UniProtKB	P	positive regulation of ureteric bud formation
GO:0009791	IEA:Ensembl	P	post-embryonic development
GO:0002572	IEA:Ensembl	P	pro-T cell differentiation
GO:0043370	IEA:Ensembl	P	regulation of CD4-positive, alpha-beta T cell differentiation
GO:2000683	IMP:UniProtKB	P	regulation of cellular response to X-ray
GO:0042035	ISS:UniProtKB	P	regulation of cytokine biosynthetic process
GO:2000114	IEA:Ensembl	P	regulation of establishment of cell polarity
GO:0061085	IEA:Ensembl	P	regulation of histone H3-K27 methylation
GO:0051569	IEA:Ensembl	P	regulation of histone H3-K4 methylation
GO:0072182	ISS:UniProtKB	P	regulation of nephron tubule epithelial cell differentiation
GO:0043523	IEA:Ensembl	P	regulation of neuron apoptotic process
GO:0010975	IEA:Ensembl	P	regulation of neuron projection development
GO:0042493	IEA:Ensembl	P	response to drug
GO:0043627	IEP:UniProtKB	P	response to estrogen
GO:0045471	IEA:Ensembl	P	response to ethanol
GO:0010332	IEA:Ensembl	P	response to gamma radiation
GO:0009615	IEP:UniProtKB	P	response to virus
GO:0007165	ISS:UniProtKB	P	signal transduction
GO:0048485	ISS:UniProtKB	P	sympathetic nervous system development
GO:0050852	ISS:UniProtKB	P	T cell receptor signaling pathway
GO:0045064	IEA:Ensembl	P	T-helper 2 cell differentiation
GO:0045061	IEA:Ensembl	P	thymic T cell selection
GO:0048538	IEA:Ensembl	P	thymus development
GO:0031929	ISS:UniProtKB	P	TOR signaling
GO:0006366	TAS:ProtInc	P	transcription from RNA polymerase II promoter
GO:0001806	IEA:Ensembl	P	type IV hypersensitivity
GO:0060676	ISS:UniProtKB	P	ureteric bud formation
GO:0035799	IEA:Ensembl	P	ureter maturation
GO:0060065	ISS:UniProtKB	P	uterus development
GO:0003281	ISS:UniProtKB	P	ventricular septum development

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_24970	Factors involved in megakaryocyte development and platelet production
REACT_604	Hemostasis