MGP Database

MGP001166

Ontology/Pathway Information

Entrez Gene ID	2628
Gene Name	glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Gene Symbol	GATM
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005743	IEA:UniProtKB-SubCell	C	mitochondrial inner membrane
GO:0005758	IDA:MGI	C	mitochondrial intermembrane space
GO:0015068	IDA:MGI	F	glycine amidinotransferase activity
GO:0016813	IEA:InterPro	F	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
GO:0034641	TAS:Reactome	P	cellular nitrogen compound metabolic process
GO:0006601	IDA:MGI	P	creatine biosynthetic process
GO:0006600	TAS:Reactome	P	creatine metabolic process
GO:0046689	IEA:Ensembl	P	response to mercury ion
GO:0007584	IEA:Ensembl	P	response to nutrient
GO:0006979	IEA:Ensembl	P	response to oxidative stress
GO:0043434	IEA:Ensembl	P	response to peptide hormone
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0042246	IEA:Ensembl	P	tissue regeneration

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_813	Creatine metabolism
REACT_111217	Metabolism
REACT_13	Metabolism of amino acids and derivatives

SMP Pathway Links

SMP ID	Description
SMP00721	3-Phosphoglycerate dehydrogenase deficiency
SMP00020	Arginine and Proline Metabolism
SMP00362	Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)
SMP00504	Creatine deficiency, guanidinoacetate methyltransferase deficiency
SMP00179	Dihydropyrimidine Dehydrogenase Deficiency (DHPD)
SMP00242	Dimethylglycine Dehydrogenase Deficiency
SMP00484	Dimethylglycinuria
SMP00004	Glycine and Serine Metabolism
SMP00188	Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency)
SMP00485	Hyperglycinemia, non-ketotic
SMP00506	Hyperornithinemia-hyperammonemia-homocitrullinuria [HHH-syndrome]
SMP00505	Hyperornithinemia with gyrate atrophy (HOGA)
SMP00361	Hyperprolinemia Type I
SMP00360	Hyperprolinemia Type II
SMP00507	L-arginine:glycine amidinotransferase deficiency
SMP00223	Non Ketotic Hyperglycinemia
SMP00363	Ornithine Aminotransferase Deficiency (OAT Deficiency)
SMP00207	Prolidase Deficiency (PD)
SMP00208	Prolinemia Type II
SMP00244	Sarcosinemia